
Glymphatic system
77
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11
EPISODES
10
PODCASTS
Search complete. 77 mentions across 11 episodes found for "Glymphatic system".
Nov 9, 2026
Ep.90, What If We're Measuring the Wrong Things? Airway, Sleep & Brain Health, Dr. Eric Phelps, DDS, MS
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26:30Eric PhelpsGUEST
And I think we end up, what I talked about last night, we end up with down-regulation of dopamine receptors.
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26:37Eric PhelpsGUEST
And then there's this issue of glymphatic drainage.
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26:43Eric PhelpsGUEST
All right.
E
26:43Eric PhelpsGUEST
So again, you learn in the suffering.
E
30:53Eric PhelpsGUEST
What's the neurophysiology? What's actually happening? And so I was in between patients one morning and I just saw this kid with ADHD and I said, I got him.
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31:04Eric PhelpsGUEST
So I I looked at Gimeno stuff and then I just got on cloud and I just started questioning things about mechanisms.
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31:17Eric PhelpsGUEST
And it was dopamine downregulation and glymphatic drainage.
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31:23Eric PhelpsGUEST
And then I just knew it.
The Most Overlooked Longevity System in Your Body
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5:03AlexHOST
They described a system of fluid channels running alongside the brain's blood vessels using glial cells, which are these sort of supporting cells for the brain, and that was sort of described as the structural framework for the brain.
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5:19AlexHOST
And we call it the glymphatic system combining glial, which is the sort of type of brain cell, with lymphatic, so glymphatic.
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5:28AlexHOST
And what this system does... is absolutely remarkable.
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5:32AlexHOST
So during your sleep, cerebrospinal fluid, so CSF, cerebrospinal fluid, which is that clear liquid surrounding your brain and your spinal cord, and it's what comes out when we do a lumbar puncture, This is actively pumped through these different channels and it's flushing metabolic waste out of your tissue as it does that.
14 MINS LATER
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20:06AlexHOST
We know that alcohol is one of the most reliably documented disruptors of your sleep architecture.
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20:13AlexHOST
How well you sleep.
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20:14AlexHOST
and even just small amounts of alcohol before bed, it reduces the proportion of deep, slow-wave sleep, which is precisely the stage when your glymphatic system sort of is working hardest.
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20:27AlexHOST
The impairment isn't dramatic after a single drink.
Professor Louise Parr-Brownlie on brain health, mātauranga Māori and the UN
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24:59Grant RobertsonHOST
REM
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25:00Louise Parr-BrownlieGUEST
... glymphatic.
G
25:00Grant RobertsonHOST
No. [laughs]
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25:01Louise Parr-BrownlieGUEST
No, no, REM sleep.
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25:02Grant RobertsonHOST
Yeah.
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25:02Louise Parr-BrownlieGUEST
But the glymphatic system, where it actually drains, um, toxins and, and bad proteins that you need to clear from your brain.
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25:11Grant RobertsonHOST
Mm.
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25:11Louise Parr-BrownlieGUEST
Um, and it only happens when you're in deep sleep, so, um, you need deep sleep.
The Glymphatic System - Can you boost your brain's deep-cleaning system to prevent Alzheimer’s?
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1:01Cat de LangeHOST
This is a really, really important topic that we're going to talk about today.
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1:06Cat de LangeHOST
And it is the glymphatic system.
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1:08Cat de LangeHOST
So not everyone would have heard of that.
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1:09Cat de LangeHOST
Helen, this was your idea.
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1:11Cat de LangeHOST
Tell us what you're thinking.
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1:13Helen ThomsonHOST
Okay, so normally I have heard about this stuff because I've got a neuroscience degree, you know, I write about it all the time, but actually the glymphatic system is fairly new and it always excites me when we suddenly find out something new about the brain.
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1:26Helen ThomsonHOST
I didn't know about this in my degree.
H
1:29Helen ThomsonHOST
It appeared like 10 years after I first studied neuroscience.
24 Hours to Unlock Maximum Cell Repair
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15:42Jin W. SungHOST
What I'm trying to teach you here is the process that occurs when you actually do the intermittent fasting and how a profound impact you can have on your body if you can catch it early enough.
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15:56Jin W. SungHOST
if you can catch alzheimer's or parkinson's disease early on and you start implementing a ketogenic diet intermittent fasting you can have a profound effect without any really taking any nutrients or supplements you can have a profound effect just on dietary intake alone how to clean the brain the glymphatic system what is it what are some of the conditions associated with it Most importantly, how do we improve the lymphatic system to improve our overall health? So let's get right into it.
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16:33Jin W. SungHOST
The lymphatic system is analogous to the lymphatic system of our body.
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16:38Jin W. SungHOST
Basically, it's the lymphatic system of our central nervous system, which is brain and spinal cord.
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18:53Jin W. SungHOST
Now, here are some of the important things that you need to do to help enhance the lymphatic system.
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19:01Jin W. SungHOST
Number one really is sleep.
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19:04Jin W. SungHOST
They've done studies on animals, And they noticed that when you have proper amounts of sleep between seven and nine hours of good deep sleep, you will have better clearance of the glymphatic system.
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19:19Jin W. SungHOST
Also sleeping on your right side is the best position to enhance the system or clear the system.
The Truth About Alzheimer's: A Genetic Certainty? Not With The Inner Well!
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23:34EmilyHOST
I want to go back to some more of the science.
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23:38EmilyHOST
And when I was doing a little research on your research, I didn't know this term before, the glymphatic system.
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23:45EmilyHOST
But could you talk a little bit about the glymphatic system and sort of what that means and how that operates in the brain? So I think it really relates to what we're talking about here.
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23:56Alarik ArenanderGUEST
If you live in the house, you have to keep things clean.
A
23:58Alarik ArenanderGUEST
Because just like things get disorderly and you have to throw things away, if you're in a kitchen, if you don't clean up, it's hard to work in the kitchen.
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24:53Alarik ArenanderGUEST
So basically...
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24:55Alarik ArenanderGUEST
During slow-wave sleep in particular, the first sort of hour of your sleep at night, or 90 minutes if you're really good at it, and then following off during the different dreaming and isolation during the night, the system is pumping out all the garbage.
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25:08Alarik ArenanderGUEST
Glymphatic system is removing all the garbage.
223. 3 Simple Ways to Support Your Lymphatic System Every Day with John Ossipinsky
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8:10John OssipinskyGUEST
Well, now we know there's a direct lymph brain connection.
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8:14John OssipinskyGUEST
And even though there's a lot of attention to the glymphatic system, that's a specific system inside your brain.
J
8:20John OssipinskyGUEST
And it's really just like a little sheath that just pulls fluid through your brain, clearing cerebrospinal fluid and waste.
J
8:25John OssipinskyGUEST
But what's important is that the glymphatic system must flow to the lymphatic system because they found lymphatic vessels right around the meninges, the meningeal lymphatic vessels.
J
8:36John OssipinskyGUEST
It's right around the brain.
J
8:37John OssipinskyGUEST
So if your lymphatic system in your neck, under your clavicles in your neck is congested, then how can your glymphatic system clear waste into your lymphatic system? And that's the point that we're missing.
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8:49John OssipinskyGUEST
So it's important to understand the glymphatic system, but the glymphatic system must flow to the lymphatic system.
J
8:56John OssipinskyGUEST
And that's why the lymphatic system always becomes more important for really everything.
Apple Watch, WHOOP & Oura: The Health Tracking Lie (You're the Product) | PT. 2
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39:40Trevor BachmeyerHOST
and three is the slow wave deep sleep listen to this one pay attention okay delta waves below 2 hertz with amplitude exceeding 75 micro volts so representing synchronized cortical neuronal down states which the glymphatic system the pressure washer for your brain your brain's lymphatic waste clearance network activates to clear tau protein, amyloid beta, all the accumulations linked to dementia, Alzheimer's disease.
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40:04Trevor BachmeyerHOST
2023, nature aging confirmed.
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40:06Trevor BachmeyerHOST
Glymphatic clearance is exclusively, oh, I got to get this out, exclusively dependent on slow wave activity.
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40:12Trevor BachmeyerHOST
It can't be inferred from any peripheral physiological measurement whatsoever.
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40:16Trevor BachmeyerHOST
how does your watch know again i'll help you it can't rem sleep okay rapid eye movement shows desynchronized low amplitude electron cephalogram eeg pattern paradoxically similar to wakefulness didn't know that did you complete skeletal muscle atonia mediated by glycinergic inhibition of motor neurons rapid conjugate eye movements visible only through electrooculography This is where memory consolidation, this is so important, memory consolidation, emotional processing, synaptic homeostasis occur through mechanisms requiring active neural monitoring to even detect.
Incorporating Lymphatic Drainage Into Treatment, with guest Jennifer
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25:41AmandaHOST
The lymphatic
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25:41MarkHOST
system of the brain? Glymphatics, yeah.
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25:43Jennifer StrukhoffGUEST
Yeah, glymphatics, yeah.
J
25:45Jennifer StrukhoffGUEST
And he talked about it last year, too.
Apple Watch, WHOOP & Oura: What These Devices Aren't Telling You About Your Health
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51:32Trevor BachmeyerHOST
2023 nature agent confirmed.
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51:33Trevor BachmeyerHOST
Glymphatic clearance is exclusively sleep stage dependent, specifically requiring deep 10 rem slow wave activity to function.
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51:42Trevor BachmeyerHOST
So when your watch incorrectly tells you that you got 47 minutes of deep sleep, when you actually got 90, you believe you have a serious sleep deficit.
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51:50Trevor BachmeyerHOST
And you know what you do? You take melatonin.
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