Glutathione

No wonder God made me a chiropractor who focuses on the nervous system instead of a medical doctor who deals in pharmacology and chemistry, okay? So researchers call it N-A-P-Q-I, all right? All you need to know is that that is the troublemaker in the whole story.

napqi is what's called a reactive metabolite and in plain english it's a hot unstable little sucker of a molecule that damages tissue if it's allowed to run loose and your body has a built-in fire extinguisher exactly for this little sucker and all the other ones that are just like it because our body gets this stuff not only from acetaminophen but different things come into the body and create these metabolites these little troublemakers just like this there's thousands of them That extinguisher that God gave our body naturally and produces on its own is called glutathione.

Glutathione is the body's master antioxidant.

You could argue one of, if not the most important molecule in the body to keep our immune system healthy.

Its job is to neutralize, cool it down, and escort that little sucker out of there safely.

out? Well, when I came across it, there were 50,000 published studies.

Glutathione was discovered in 1888.

Nobody really studied it until about 1984.

By 1990, there were 16,000 published studies.

And that's what happens.

That's glutathione.

Glutathione impacts every aspect from the skin, the eyes, the liver, the kidneys, everything.

The immune system, how fast your immune system can respond to a viral or bacterial invasion is entirely dependent on glutathione because it is the protector of the T cells.

As ROS levels continue to rise, the liver's antioxidant defenses become overwhelmed.

One of the most critical antioxidants affected is mitochondrial glutathione, or GSH, which serves as the liver's primary intracellular defense system against oxidative damage.

Depletion of GSH promotes lipid peroxidation, damaging cellular membranes and impairing liver function.

At the same time, ROS activates stress-related signaling pathways such as JNK and AP1, further amplifying inflammation and oxidative injury within the liver.

In addition, excessive ROS suppresses the activity of NRF2, a major protective transcription factor responsible for regulating antioxidant responses and cellular defense mechanisms, This is where curcumin, the active bioactive compound in turmeric, becomes particularly important.

Okay, so this is what, according to MD Andrews-Weich, this is what he's saying.

Tylenol reduces glutathione.

Glutathione is a tripeptide.

So this is glycine, cysteine, and glutamate, just so you're aware.

Glutathione is an antioxidant that highly mitigates inflammatory damage.

So when you have inflammation, that's your body.

Like if you get sick, your body produces inflammation.

The whole idea is that inflammation is supposed to kill off that pathogen.

Right.

And when you have mercury poisoning, it makes it much, much harder to benefit from a fast because so many metabolic pathways are basically ruined and not functional due to enzyme inhibition that you're not producing glutathione.

You're not detoxifying readily.

So you end up being – it's a much more serious situation that has to be taken at a much more gradual pace.

And, which, you know, if I'd had this One World Whey Protein Powder back then and I knew about it, that would have been the more gradual thing to do.

If I would have done the whey protein, I would have been able to have raised my glutathione and detoxified my body with mercury and, you know, my whole life would have been a different story.

But, you know, things are what they are.

Yeah.

You understand what I just said? Just one of the common intermediates.

So [chuckles] and it works not directly because it controls the glutathione peroxidase, which controls the level of reactive oxygen by utizing- using glutathione through its redox, right? GSH to GSSG, after all.

Okay? So not only that, coenzyme Q, which is a quinoid, which is also coming from isoprenoid biosynthesis, and an intermediate in cholesterol biosynthesis called squalene.

So you have the quinoids like coenzyme Q and squalene.

I have always wondered about the evidence around supplements and how supplements come into play.

One of the big time supplements that's had a lot of press, a lot of interest is glutathione.

And who else but to better talk to than the person who's written the book called The Glutathione Revolution, Dr. Nayan Patel.

He's a pharmacist, wellness expert, He is the founder of RO Wellness and CEO of Central Drugs Compounding Pharmacy.

So he knows a thing or two about how to use these ingredients in a few places.

So we have two-part technology.

I had to get the glutathione through your skin.

Glutathione is a very large molecule, roughly between 50 to 80 nanometers in size.

It absorbs transdermally.

Glutathione is our body's most potent antioxidant and anti-inflammatory agent.

So much of Hashimoto's is influenced by inflammation.

So we can reduce inflammation going in or improve our way of dealing with inflammation, combating it or getting rid of it.

Glutathione's a powerful mechanism for that.

Even selenium also is a form of an antioxidant, anti-inflammatory.

Um, you can change your diet for sure, and I can go as deep into that as you want.