GJA1

From the single-cell sequencing, we have noted the upregulation of several contractility-associated genes is impaired in the not-called animals.

And we confirmed this with incentive hybridization, shown here of the mouse uterine sections at gestational day 18.5, indicating that the gap junction, the CX43 transcript, is downregulated in the double knockout animals, which is one of the contractility-associated genes, and associated with uterine contractions at the time of labor.

With all these observations, I have shown that the mechanosensing mediated by the piezo seemed to be really contributing strongly, is a strong contributor to the uterine contractions at the time of labor.

And piezo is only like the first step into the study of the mechanosensation during the whole pregnancy and perpetuation steps.

From the single-cell sequencing, we have noted the upregulation of several contractility-associated genes is impaired in the piece of knockout animals.

And we confirm this with incentive hybridization, shown here of the mouse uterine sections at gestational day 18.5, indicating that the gap junction, the CX43 transcript, is downregulated in the double knockout animals, which is one of the contractivity-associated genes, and associated with uterine contractions at the time of labor.

With all these observations, I have shown that the mechanosensors mediated by the piezo seem to be really contributing, is a strong contributor to the uterine contractions at the time of labor.

And piezo is only like the first step into the study of the mechanosensation during the whole pregnancy and perpetuation steps.