G0 phase

The G1 phase, which marks the beginning of a cell's life, involves cell growth.

Some cells divide very infrequently, or not at all, so cells can spend a long time in this phase, or a related phase called G0.

Other cells that divide more rapidly may spend only a few hours in this phase.

In adult humans, the S phase takes ten to twelve hours, and as we said, results in two identical copies of the genome.

There is also a checkpoint during the G1 phase that is called the restriction point.

This is a stop point that must be overridden by a signal in order to continue to the rest of the cycle.

In absence of this signal, the cell remains in the G1 phase, or moves into the G0 phase, which is a non-dividing state.

Most of our cells are in the G0 phase at any given time, but these can be called back into the cell cycle by external signals like growth factors, which can be released during injury to stimulate cell growth to heal the wound.

So then the cell just dies because it's become distorted.

Cyrolimus and everolimus drugs, on the other hand, they are affecting the cell in the cell cycle at an earlier stage between the G0, G1 going to the S phase.

So they stop the cell from going into the S phase.

So it's more of a cytostatic drug.