
Frederick Beddingfield
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Sep 2, 2026
862: Reversing Cellular Senescence: GPX4, Ferroptosis, and Adaptive Senotherapeutics with Dr. Frederick Beddingfield
K
4:35KayHOST
And what is this peroxidation concept that we're not that familiar with?
4:49
And it's known as a key component of something called ferrooptosis, which is this iron-dependent cell death.
4:57
But now we're coming to understand it's involved in free radical suppression and the whole redox state of the cell.
5:06
And so it turns out to have downstream effects on all the functions of the cell.
5:10
We think we, you know, through our AI platform, this came out, this target GPX4.
16 MINS LATER
K
20:52KayHOST
So is this going to help patients hopefully with neurodegenerative disorder where the brain is made of myelin and there's peroxidation damage for Alzheimer's and
