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Search complete. 2 mentions across 2 episodes found for "FBXW7".

Oct 2, 2026

Dave AspreyHOST
4:17
They also found changes involving MYC, PTEN, PIK3CA, and several other pathways anybody who follows oncology will recognize.
Dave AspreyHOST
4:27
One of the more interesting findings was in feline mammary cancer, where mutations in a gene called FBXW7 showed up in a large percentage of tumors.
Dave AspreyHOST
4:37
Researchers then grew a tiny number of these tumors in three-dimensional models and found that the ones carrying the mutation responded differently to certain chemotherapy drugs.
Dave AspreyHOST
4:47
What interests me is the model itself.
Oren GiladGUEST
9:34
Then we have mutation independent of the indication.
Oren GiladGUEST
9:37
That's the PPP2R1A, FBXW7, cyclin E.
Oren GiladGUEST
9:42
Those patients that have, it can be prostate cancer, it can be breast cancer, it can be other tumor types, but they have to carry this mutation.
Oren GiladGUEST
9:51
The third strategy is specific indication with a specific mutation.

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