NR1H4

Could we see a near future where a defense attorney argues in court that a severe documented state of dysbiosis temporarily robbed their client of impulse control? Wow.

Imagine a legal defense built on the premise that a compromised FXR-TGR5 bile acid pathway hijacked the defendant's frontostriatal dopamine networks, effectively negating their intent.

It sounds like science fiction today, but as the mechanistic proof of the gut-brain axis becomes undeniable, our rigid legal definitions of culpability and free will are going to face a very difficult biological reality.

It really makes you wonder who is actually steering the ship.