Delta sleep-inducing peptide

But the key thing is this.

They grab it and they go, wow, so what is DSIP? It's Delta Sleep Inducing Peptide.

This is something that helped my wife get off of her sleeping aids.

Ambien, you know, is a gnarly drug.

I mean, it tells you, may, you know, experience hallucinations, may make you want to, you know, take your own life.

That's pretty insane as a side effect.

So this DSIP, the peptide that I'm talking about now, it's non-addictive.

I don't care if you're on a sleeping aid or not.

Well, I mean, I think that's fantastic.

And I think also DSIP also could affect luteinizing hormones.

So there's a little bit of concern about this for sleep, but I'm jacking up luteinizing hormones.

And if I'm not accounting for that, and someone's already on hormone replacement, or maybe they're on a clomiphene or HCG, what's that mean? So I think that DSIP didn't cut the mustard on it.

At the same time, C-Max, that was approved and that was for mood.

Helps with anxiety, helps with focus.

And hence the When people, when you interview enough people that have been on them, they go, oh, wow, I feel really froggy when I wake up, even though I stayed asleep.

Is that

It's worth thinking a little bit about the 2026 regulatory story that probably sort of starts in 2023, when the FDA placed a batch of popular peptides in what is called category two, which means significant safety risks, citing immunogenicity, peptide-related impurities and limited safety information.

That list included peptides that we will talk about, BPC-157, DSIP, that is imidlatide and epitilon.

These are all in that sort of category two significant safety risk information.

In April of 2026, the FDA removed 12 peptides from Category 2 after the nominations were withdrawn.

The removal did not make them compoundable.

And in July of 20, in July of 2026, the FDA's Pharmacy Compounding Advisory Committee voted on seven peptides and recommended six, BPC-157, KPV, TB-500, MOTS-C, CMAX, and the one I just mentioned for Epidolon, reportedly over FDA staff's objections.

The only one that was rejected was the DSIP, which is ironic because that was the one that was literally named after deep sleep.

And that was the one that the committee really didn't want to back.

It wasn't...

And it was BPC-157, Selank, all the fun stuff, MOTS-c, DSIP, or, like, seven or eight, I can't remember the, all of them, but it was more we're advising that you allow us to compound it.

Okay.

But for what? But we don't know what biological indication for, but we're advising you, and then the biological indication they discussed, particularly with BPC-157, was on ulcerative colitis.

You've got Selank and Semax for prefrontal cortex and controlling your amygdala and getting your brain fog down.

Mm.

You've got DSIP for sleeping.

You've got, uh, PT-141 for, to drive a little bit of sex or Kisspeptin, right? Like, there's so many different peptides, but my, the, the reason why I get a little bit passionate about this, and you've seen me passionate on stages-

HGH actually helps too.

Um, so CJC, ipamorelin, even sermorelin, um, DSIP, and epitalon.

Those are options there.

Yeah.

Um, I think you would.

Like he said, the Wolverine should be your best friend.

DSIP, in my opinion, should be your best friend.

You're probably-

So the research does connect this to declining, uh, melatonin and the production that comes from that, and disrupted, uh, circadian rhythm, your body's internal 24-hour clock.

So the peptides that I have covered that address DSIP, which is a peptide your body naturally produces specifically involved in sleep regulation, and I covered it in my Meet DSIP episode.

So another one I've talked about is Epitalon, which I published an episode on as well.

It's derived from the pineal gland, the same gland that produces the melatonin.

You go deepen into your REM sleep.

So literally D-Sip.

It's D-Sip, S-I-P.

That is literally for deep sleep.

It's not gonna give you that, like, groggy NyQuil melatonin feel.

You're literally just getting more restful sleep, staying in REM longer, and all of those sleep cycles that, like, really help you recover.

Yeah.

A lot of people, athletes, um, anyone who's, like, just pushing hard in the gym, they, uh, they'll all take D-Sip 'cause that's gonna just help you get the most out of the time that you're sleeping.