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David Planchard

David Planchard

Search complete. 10 mentions across 8 episodes found for "David Planchard".

Oct 9, 2026

Enriqueta FelipHOST
1:57
We also commented the need for HER2 overexpression testing by immunohistochemistry.
Enriqueta FelipHOST
2:03
Uh, in the second episode, uh, together with, uh, David Planchard, we highlighted the results in HER2-mutant patients, uh, with ADCs and TKIs, and we also discussed the activity of these agents even in presence of brain metastases.
Enriqueta FelipHOST
2:20
And we also discussed the EMA's, uh, recent approval of, uh, trastuzumab deruxtecan for patients with HER2 overexpression 3+ on an agnostic basis.
Enriqueta FelipHOST
2:30
Uh, but we still, uh, face some challenges, no? Unmet needs, uh, uh, of treatment.
Enriqueta FelipHOST
2:47
So, uh, Egbert, uh, what are the most relevant studies, uh, currently being conducted in patients with non-small cell lung cancer, uh, with HER2 mutations?
Egbert SmitGUEST
2:59
So I think, um, we have-- we already have seen the results of, um, these novel small molecule tyrosine kinase inhibitors, like son- son德尼尼b and sifu德尼尼b, in patients who have been... already been treated, pretreated with chemotherapy plus or minus immunotherapy.
Egbert SmitGUEST
3:20
And the same applies to this, um, uh, ADC called trastuzumab deruxtecan, which also has had, as David Planchard obviously has told you, um, has significant activity in patients with either a HER2 mutant or HER2 overexpressing non-small cell lung cancer that has been treat-- pretreated with chemotherapy plus or minus immunotherapy.
Egbert SmitGUEST
3:46
So the most important question now is: Do these agents have similar or even superior activity against, uh, HER2 mutant non-small cell lung cancer in the metastatic setting in the first-line treatment? And, um, a couple of studies are, um, already recruiting patients for some time and are expected to be, uh, to report, um, very soon.
Enriqueta FelipHOST
0:50
Today, we will discuss how to integrate, uh, the HER2-targeted therapies into treatment pathways in non-small cell lung cancer, how to incorporate, uh, real-world factors such as, uh, patient eligibility, comorbidities, and performance status, and importantly, how to monitor and manage, uh, toxicities such as interstitial lung disease and gastrointestinal events.
Enriqueta FelipHOST
1:16
So and it's a true honor to be able to share, uh, the data and experiences, uh, regarding therapeutic approaches, uh, for HER2-positive patients with Dr. David Planchard.
Enriqueta FelipHOST
1:29
Uh, David, if you could please introduce yourself.
David PlanchardGUEST
1:32
Hello, Enriqueta.
David PlanchardGUEST
1:33
Hello, hello, everyone.
David PlanchardGUEST
1:34
So David Planchard.
David PlanchardGUEST
1:35
So I'm thoracic oncologist.
David PlanchardGUEST
1:37
I'm working at, uh, Gustave Roussy, Villejuif, France, and mainly taking care of patient, uh, with lung cancer, non-small cell, uh, but also mesothelioma.
Egbert SmitGUEST
34:45
Yes.
Egbert SmitGUEST
34:46
So the next speaker will be our chair, uh, Professor David Planchard, implementing optimal ca- optimal care in addressing AEs in HER2 overexpressing non-small cell lung cancer.
David PlanchardMODERATOR
34:57
Thanks so much, Egbert Jordans.
David PlanchardMODERATOR
34:58
[audience applauding] So, uh, let's move about potential toxicity and particularly the ILD.
Egbert SchimmelGUEST
34:45
Yes.
Egbert SchimmelGUEST
34:46
So the next speaker will be our chair, uh, Professor David Planchard, implementing optimal ca-- optimal care and addressing AEs in HER2 overexpressing non-small cell lung cancer.
David PlanchardMODERATOR
34:57
Thanks so much, Egbert Solecht.
David PlanchardMODERATOR
34:58
[clapping] So let's move about potential toxicity and particularly the ILD.
Egbert SmitGUEST
34:46
So the next speaker will be our chair.
Egbert SmitGUEST
34:49
Professor David Planchard, Implementing Optimal Mental Care and Addressing A.E.s in her two over-expression, non-spontaneous...
David PlanchardMODERATOR
35:03
So let's move about potential toxicity, and particularly the ILD.
David PlanchardMODERATOR
35:07
First, you can scan the QR code, question patient metastatic non-small cell lung cancer receiving TdXD 5.4 mg per kick and has an ongoing tumor response.
Egbert SmitGUEST
34:46
So the next speaker will be our chair.
Egbert SmitGUEST
34:49
Professor David Planchard, Implementing Optimal Care and Addressing A.E.s, in her two overexpression, non-sponsored, long-term.
Egbert SmitGUEST
34:57
Thank
David PlanchardMODERATOR
34:57
you.
Egbert SmitGUEST
34:46
So the next speaker will be our chair.
Egbert SmitGUEST
34:49
Professor David Planchard, Implementing Optimal Mental Care and Addressing A.E.s in her two over-expression, non-spontaneous...
David PlanchardMODERATOR
35:03
So let's move about potential toxicity, and particularly the ILD.
David PlanchardMODERATOR
35:07
First, you can scan the QR code, question patient metastatic non-small cell lung cancer receiving TdXD 5.4 mg per kick and has an ongoing tumor response.
Egbert SmitGUEST
34:45
Yes.
Egbert SmitGUEST
34:46
So the next speaker will be our chair, uh, Professor David Planchard, implementing optimal car- optimal care and addressing AEs in HER2 overexpressing non-small cell lung cancer.
David PlanchardHOST
34:57
Thanks so much, Egbert Solecht.
David PlanchardHOST
34:58
[audience applauding] So let's move about potential toxicity and particularly the ILD.

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