
David Planchard
10
MENTIONS
8
EPISODES
7
PODCASTS
Search complete. 10 mentions across 8 episodes found for "David Planchard".
Oct 9, 2026
Future directions in HER2-positive NSCLC | S14E3
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1:57Enriqueta FelipHOST
We also commented the need for HER2 overexpression testing by immunohistochemistry.
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2:03Enriqueta FelipHOST
Uh, in the second episode, uh, together with, uh, David Planchard, we highlighted the results in HER2-mutant patients, uh, with ADCs and TKIs, and we also discussed the activity of these agents even in presence of brain metastases.
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2:20Enriqueta FelipHOST
And we also discussed the EMA's, uh, recent approval of, uh, trastuzumab deruxtecan for patients with HER2 overexpression 3+ on an agnostic basis.
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2:30Enriqueta FelipHOST
Uh, but we still, uh, face some challenges, no? Unmet needs, uh, uh, of treatment.
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2:47Enriqueta FelipHOST
So, uh, Egbert, uh, what are the most relevant studies, uh, currently being conducted in patients with non-small cell lung cancer, uh, with HER2 mutations?
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2:59Egbert SmitGUEST
So I think, um, we have-- we already have seen the results of, um, these novel small molecule tyrosine kinase inhibitors, like son- son德尼尼b and sifu德尼尼b, in patients who have been... already been treated, pretreated with chemotherapy plus or minus immunotherapy.
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3:20Egbert SmitGUEST
And the same applies to this, um, uh, ADC called trastuzumab deruxtecan, which also has had, as David Planchard obviously has told you, um, has significant activity in patients with either a HER2 mutant or HER2 overexpressing non-small cell lung cancer that has been treat-- pretreated with chemotherapy plus or minus immunotherapy.
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3:46Egbert SmitGUEST
So the most important question now is: Do these agents have similar or even superior activity against, uh, HER2 mutant non-small cell lung cancer in the metastatic setting in the first-line treatment? And, um, a couple of studies are, um, already recruiting patients for some time and are expected to be, uh, to report, um, very soon.
Practical considerations for implementation of HER2-targeted therapies | S14E2
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0:50Enriqueta FelipHOST
Today, we will discuss how to integrate, uh, the HER2-targeted therapies into treatment pathways in non-small cell lung cancer, how to incorporate, uh, real-world factors such as, uh, patient eligibility, comorbidities, and performance status, and importantly, how to monitor and manage, uh, toxicities such as interstitial lung disease and gastrointestinal events.
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1:16Enriqueta FelipHOST
So and it's a true honor to be able to share, uh, the data and experiences, uh, regarding therapeutic approaches, uh, for HER2-positive patients with Dr. David Planchard.
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1:29Enriqueta FelipHOST
Uh, David, if you could please introduce yourself.
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1:32David PlanchardGUEST
Hello, Enriqueta.
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1:33David PlanchardGUEST
Hello, hello, everyone.
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1:34David PlanchardGUEST
So David Planchard.
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1:35David PlanchardGUEST
So I'm thoracic oncologist.
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1:37David PlanchardGUEST
I'm working at, uh, Gustave Roussy, Villejuif, France, and mainly taking care of patient, uh, with lung cancer, non-small cell, uh, but also mesothelioma.
Prof. David Planchard, MD, PhD - From Data to Decisions in HER2-Overexpressing NSCLC: Detecting Alterations, Implementing Therapeutic Advances, and Navigating Practicalities of Care
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34:45Egbert SmitGUEST
Yes.
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34:46Egbert SmitGUEST
So the next speaker will be our chair, uh, Professor David Planchard, implementing optimal ca- optimal care in addressing AEs in HER2 overexpressing non-small cell lung cancer.
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34:57David PlanchardMODERATOR
Thanks so much, Egbert Jordans.
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34:58David PlanchardMODERATOR
[audience applauding] So, uh, let's move about potential toxicity and particularly the ILD.
Prof. David Planchard, MD, PhD - From Data to Decisions in HER2-Overexpressing NSCLC: Detecting Alterations, Implementing Therapeutic Advances, and Navigating Practicalities of Care
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34:45Egbert SchimmelGUEST
Yes.
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34:46Egbert SchimmelGUEST
So the next speaker will be our chair, uh, Professor David Planchard, implementing optimal ca-- optimal care and addressing AEs in HER2 overexpressing non-small cell lung cancer.
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34:57David PlanchardMODERATOR
Thanks so much, Egbert Solecht.
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34:58David PlanchardMODERATOR
[clapping] So let's move about potential toxicity and particularly the ILD.
Prof. David Planchard, MD, PhD - From Data to Decisions in HER2-Overexpressing NSCLC: Detecting Alterations, Implementing Therapeutic Advances, and Navigating Practicalities of Care
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34:46Egbert SmitGUEST
So the next speaker will be our chair.
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34:49Egbert SmitGUEST
Professor David Planchard, Implementing Optimal Mental Care and Addressing A.E.s in her two over-expression, non-spontaneous...
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35:03David PlanchardMODERATOR
So let's move about potential toxicity, and particularly the ILD.
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35:07David PlanchardMODERATOR
First, you can scan the QR code, question patient metastatic non-small cell lung cancer receiving TdXD 5.4 mg per kick and has an ongoing tumor response.
Prof. David Planchard, MD, PhD - From Data to Decisions in HER2-Overexpressing NSCLC: Detecting Alterations, Implementing Therapeutic Advances, and Navigating Practicalities of Care
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34:46Egbert SmitGUEST
So the next speaker will be our chair.
E
34:49Egbert SmitGUEST
Professor David Planchard, Implementing Optimal Care and Addressing A.E.s, in her two overexpression, non-sponsored, long-term.
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34:57Egbert SmitGUEST
Thank
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34:57David PlanchardMODERATOR
you.
Prof. David Planchard, MD, PhD - From Data to Decisions in HER2-Overexpressing NSCLC: Detecting Alterations, Implementing Therapeutic Advances, and Navigating Practicalities of Care
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34:46Egbert SmitGUEST
So the next speaker will be our chair.
E
34:49Egbert SmitGUEST
Professor David Planchard, Implementing Optimal Mental Care and Addressing A.E.s in her two over-expression, non-spontaneous...
D
35:03David PlanchardMODERATOR
So let's move about potential toxicity, and particularly the ILD.
D
35:07David PlanchardMODERATOR
First, you can scan the QR code, question patient metastatic non-small cell lung cancer receiving TdXD 5.4 mg per kick and has an ongoing tumor response.
Prof. David Planchard, MD, PhD - From Data to Decisions in HER2-Overexpressing NSCLC: Detecting Alterations, Implementing Therapeutic Advances, and Navigating Practicalities of Care
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34:45Egbert SmitGUEST
Yes.
E
34:46Egbert SmitGUEST
So the next speaker will be our chair, uh, Professor David Planchard, implementing optimal car- optimal care and addressing AEs in HER2 overexpressing non-small cell lung cancer.
D
34:57David PlanchardHOST
Thanks so much, Egbert Solecht.
D
34:58David PlanchardHOST
[audience applauding] So let's move about potential toxicity and particularly the ILD.