Dapsone
MedicationWikipedia
82
MENTIONS
8
EPISODES
8
PODCASTS
Search complete. 82 mentions across 8 episodes found for "Dapsone".
Sep 19, 2026
Episode 580: Can Treating Lyme Disease Reverse Alzheimer’s Biomarkers? Dr. Richard Horowitz’s New Study
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2:37Richard HorowitzGUEST
And then this Alzheimer's biomarker showed up and I said to her, listen, I'm finishing one-on-one clinical practice in the next few months.
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2:44Richard HorowitzGUEST
You've never done Dapsone combination therapy.
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2:47Richard HorowitzGUEST
I said, I have no idea whatsoever whether this is gonna work and reverse it.
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2:51Richard HorowitzGUEST
I just know that you do not wanna have this biomarker going forward because it could affect cognition.
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2:56Richard HorowitzGUEST
Cause she was thinking my meditation practice was explaining why I have good cognition.
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3:01Richard HorowitzGUEST
I gave her the nine week Dapsone protocol.
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3:04Richard HorowitzGUEST
We rechecked her Alzheimer's biomarkers three months later.
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3:07Richard HorowitzGUEST
Lo and behold, we reversed the biomarker, P tau sub 17.
Resilience, Purpose & Chronic Illness: Ali Moresco's Journey from Lyme Patient to Advocate, Episode #93
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20:05Ali MorescoGUEST
I became a patient of Dr. Richard Horowitz, who does DAP zone therapy.
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20:12Ali MorescoGUEST
And, um, that for me really Dapsone therapy changed everything.
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20:19Ali MorescoGUEST
Um, so I did, I believe it was a four week course of like, quote unquote, regular Dapsone therapy.
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20:27Ali MorescoGUEST
And then I did a two week course of double Dapsone and a four day pulse of quad Dapsone.
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20:36Ali MorescoGUEST
And then I also have Babiesia and Bartonella.
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20:40Ali MorescoGUEST
And for those of us with co-infections, his rule of thumb and what his research has showed is that you need, I believe it's four double dapsone pulses for the co-infections.
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21:22Ali MorescoGUEST
And I mean, it was, it was a process, you know, it was a couple of years of the DAP zone on and off and then letting my body heal and, you know, building it up and coupled with, you know, the, the sub QIG, the immune globulins.
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21:37Ali MorescoGUEST
But for me, that's, that's what did it.
Lyme Disease, Mold Illness and Emerging Therapies with Dr. Eric Potter
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18:51Eric PotterGUEST
Now, it has to be used IV, so it's not ready for oral, prime time, everyday use, but... seeing that they're actually finding better success with that.
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19:00Eric PotterGUEST
There are those who have looked at things like Dapsone, Dasulfiram, actual research studies, not just, oh, let's do a case report of 10, but true major medical centers who are looking for answers.
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19:13Eric PotterGUEST
Again, I would argue that they're Not looking under all the right rocks to turn over, but at least they've started.
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19:21Eric PotterGUEST
With that, as they find things that we've been saying outside of medicine when we're taking care of patients, and we've been saying these things for years, even before me, people who have been practicing medicine longer than I have, have been saying this, and we're finding out that the studies are proving it.
14: The Smartest Doctor in the Room with Dean Mitchell, MD - Episode 14
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24:30Richard HorowitzGUEST
Would you like me to check? And she said, okay, but don't tell me.
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24:33Richard HorowitzGUEST
Just tell me if I have to do Dapsone.
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24:35Richard HorowitzGUEST
I said, okay.
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24:36Richard HorowitzGUEST
So she came back and her P tau was high.
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24:46Richard HorowitzGUEST
You don't have rheumatoid arthritis.
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24:47Richard HorowitzGUEST
And now I'm showing inflammation in your brain.
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24:50Richard HorowitzGUEST
I need you to do Dapsone.
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24:51Richard HorowitzGUEST
She did the nine week protocol.
302. The Antibiotics That Reversed Alzheimer's Blood Marker - Dr. Richard Horowitz
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23:41Richard HorowitzGUEST
You mean it persists like tuberculosis and leprosy.
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23:44Richard HorowitzGUEST
Now, how do they cure leprosy? Rifampin and dapsone for a year.
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23:48Richard HorowitzGUEST
What did I do? I looked at the qualities of this drug called Dapsone.
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23:52Richard HorowitzGUEST
So Dapsone number one is anti-inflammatory.
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23:54Richard HorowitzGUEST
And as we're about to discuss during this podcast, every disease we're going to talk about today, ADD, ADHD, autism spectrum disorder, Alzheimer's disease, allergies and asthma, autoimmune diseases, rheumatoid arthritis, chronic fatigue syndrome, fibromyalgia, cancer, cardiovascular disease, digestive disorders, irritable bowel, inflammatory bowel, hormonal disorders, mood disorders, pain.
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24:19Richard HorowitzGUEST
Every one of them has all 16 inflammatory factors on the MSIDS model that I discovered in Lyme.
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25:15Richard HorowitzGUEST
Your immune system doesn't work.
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25:17Richard HorowitzGUEST
You develop liver disease with fatty liver disease, driving metabolic syndrome and liver inflammation, as well as pain syndromes and mood disorders.
Best of: Is It Really Fibromyalgia, MS, or Chronic Fatigue? – What Doctors Overlook with Dr. Richard Horowitz | E174
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9:58Richard HorowitzGUEST
It's the same thing.
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9:59Richard HorowitzGUEST
So once we started using biofilm agents and persister drugs, like used for tuberculosis and leprosy, that's how I came to Dapsone, we started seeing honestly miraculous results where we did not have to leave people on antibiotics forever.
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10:12Richard HorowitzGUEST
So it's about three decades for me constantly being in the trenches, just digging.
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10:18Richard HorowitzGUEST
to figure out what was keeping these people ill and you know now i'm going to be applying for nih grants myself this coming year and hopefully we'll get a randomized controlled double-blind placebo trial on dapsone so i can prove to the world that actually we do have answers
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13:53Richard HorowitzGUEST
So essentially what's happening is people's immune systems are getting overwhelmed and then you've got mold toxins like gliotoxins that are making the whole thing worse on top of all the heavy metals and other toxins where people's detox pathways aren't working.
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14:06Richard HorowitzGUEST
Mm-hmm.
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14:06Richard HorowitzGUEST
So now, whereas I'd say probably six years ago, we were finding Dapsone, of course, was working quite well.
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14:12Richard HorowitzGUEST
And we kept tweaking it year after year.
194: Dr. Mark Hyman: Why You're Still Sick—Finding the Root Cause With Functional Medicine
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40:33Mark HymanGUEST
it can actually cause a lot of neurodegenerative symptoms.
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40:37Mark HymanGUEST
He, he, he just showed, uh, through a trial using, uh, Dapsone and some other drugs in patients with Alzheimer's and high levels of a thing called p-tau217-
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40:46Darshan ShahHOST
Hmm
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40:47Mark HymanGUEST
... which is a biomarker-
Urticaria as a Systemic Disease
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19:36Torsten ZuberbierHOST
... option, um, to help these patients.
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19:39Torsten ZuberbierHOST
I also, uh, use sometimes Dapsone and petoxiflin.
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19:43Marta FerrerGUEST
Right.
T
19:43Torsten ZuberbierHOST
But these are not been tested in large scale studies.