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Cushing's syndrome

Cushing's syndrome

SyndromeWikipedia

Search complete. 106 mentions across 34 episodes found for "Cushing's syndrome".

Oct 30, 2026

Nic de BrauwereGUEST
26:53
Paying attention to the change in who they are is, I think, an important warning sign.
Nic de BrauwereGUEST
27:00
I did quite a few post mortems on horses when the vet world first learnt about Cushing's disease and where we assigned most of them to expecting to find a tumour at the pituitary gland.
Nic de BrauwereGUEST
27:14
And with tumors, you normally assume that they become bigger.
Nic de BrauwereGUEST
27:18
And I think we've since learned that PPID is often not necessarily down to a tumor that you could find if you open the brain.
Nic de BrauwereGUEST
27:25
But we certainly found quite a few horses where that was absolutely the case.
Nic de BrauwereGUEST
27:29
And then you have to recognize that that tumor then takes up space, which presses on the optic nerve.
Nic de BrauwereGUEST
27:35
So losing vision is something that people have described with Cushing's horses.
Nic de BrauwereGUEST
27:40
And also potentially if it's pressing on the brain, it could be causing headaches or other abnormal functions so that if they're not feeling themselves, there could be a physical reason for it that you can't see.
Ken BerryHOST
22:59
Here's Anna.
Ken BerryHOST
23:00
I have Cushing's disease.
Ken BerryHOST
23:01
I'm down over 200 pounds, but my cortisol is making it hard.
Ken BerryHOST
23:09
Any suggestions? Anna's lost 200 pounds and she's worried that she's not doing good enough.
Ken BerryHOST
23:16
Of course, your cortisol levels with having Cushing's disease is going to make it harder for you to lose weight, but you've already established a very successful track record and a Just keep doing what you're doing.
Ken BerryHOST
23:29
What's going to happen is your weight loss is going to be slower.
Ken BerryHOST
23:32
Just like for menopausal women, that their hormones are fluctuating and messed up.
Eric BergHOST
2:15
or your insulin is too high.
Eric BergHOST
2:17
People that have high cortisol, there's a condition called Cushing syndrome.
Eric BergHOST
2:22
They develop this.
Eric BergHOST
2:23
They actually have a fat pad on their back.
Susanne KuckuckGUEST
4:19
And when that stays in our body for a longer period, that can actually lead to a wide variety of cardiometabolic health problems.
Susanne KuckuckGUEST
4:29
So a very clinical example for what happens with long-term cortisol overexposure is what we see in patients with Cushing's disease.
Susanne KuckuckGUEST
4:40
So in patients with Cushing's disease, we see that over a very long time period, be it weeks or months or years even, basically until somebody is diagnosed, this person will be exposed to very, very high levels of cortisol.
Susanne KuckuckGUEST
4:53
And in these people, we really see that they develop insulin resistance, possibly diabetes.
Susanne KuckuckGUEST
4:59
They also have an increased risk for cardiovascular disease.
Emily KingHOST
45:05
yeah.
Emily KingHOST
45:06
I think this is a place where AI can serve like some sort of purpose, you know, like take, everything you know about Cushing's disease and put it in and be like, this is what I know as Cushing's.
Emily KingHOST
45:18
And you type it in, right? All your scientific words and all that and be like, how would how should I best explain this to a client? Yeah.
Emily KingHOST
45:25
How should I best explain this to a kid? How would I explain this to whatever? You know what I mean? And then see what it's saying and look at the word choices that it's using.
Elisha EdwardsHOST
25:21
A horse that seems a bit dull, one of the things that I see without a doubt is a lot of fatigue and depression.
Elisha EdwardsHOST
25:30
Now that is another conversation for another day, but that comes up with Cushing's, right? So a lot of those hormone changes can cause that, but horses get really tired when they have a low thyroid.
Elisha EdwardsHOST
25:42
And that's sort of one of my first sort of clues that we need to sort of focus on that metabolic rate because the body is just so tied up trying to detoxify and trying to generate what it needs to.
Elisha EdwardsHOST
25:56
So you're looking for that flat, low energy sort of feel.
Elisha EdwardsHOST
26:08
So the texture of the hair coat will change.
Elisha EdwardsHOST
26:11
And of course, slow to shed out or grow in.
Elisha EdwardsHOST
26:14
And again, that can be a bit of a Cushing's picture as well.
Elisha EdwardsHOST
26:17
Like those are clinical signs that you're looking for with Cushing's, but that's all hormone related too.
Kathryn ChristiesonHOST
32:10
So if they're over the age of about 12 or so and they're repeatedly getting abscesses, I'm going to recommend that we do that.
Kathryn ChristiesonHOST
32:18
Cushing's test.
Kathryn ChristiesonHOST
32:21
A lot of them is thoroughbreds.
Kathryn ChristiesonHOST
32:24
Just
Molly OstranderHOST
3:11
But I think that gets blown out of proportion when it comes to things like cortisol face, cortisol belly, you know, you can't blame everything on that.
Molly OstranderHOST
3:20
And you know the cortisol face thing that one's pretty concerning to me because cortisol face usually doesn't show up unless you have Cushing's like that's that's
Lara DilkesHOST
3:30
not really on high dose prednisone or prednisone
Molly OstranderHOST
3:32
yes exactly because it's
Molly OstranderHOST
4:16
Right.
Molly OstranderHOST
4:16
That's not.
Molly OstranderHOST
4:17
And I mean, Cushing's and prednisone are very situational and an actual real diagnosis that your Western doctor should be having a conversation with you about.
Molly OstranderHOST
4:26
That doesn't mean that the low grade fight or flight that you experience while you are actually gaining weight, maybe actually gaining weight in your face is changing, might be the combination that's happening.
Melissa MagsaysayHOST
7:44
But what typically are the remedies for that? Can it just be lifestyle change? Well, it depends.
Eva CwynarGUEST
7:49
Again, if we're identifying... real abnormality that's considered Cushing's.
Eva CwynarGUEST
7:56
And then we look to see if it's something called Cushing's disease or Cushing's syndrome.
Eva CwynarGUEST
8:02
One comes from the adrenal glands.
Eva CwynarGUEST
8:05
And then the other one is whether or not something is going on in the pituitary.
Eva CwynarGUEST
8:09
And these things are not cancers, they're growths generally.
Eva CwynarGUEST
8:13
So we either... cut it out or give you medicine for that.
Eva CwynarGUEST
8:18
What I think society is going through right now is something called pseudo Cushing's where you can look like Cushing's.
Scott LuperHOST
21:46
If you're making way too much hormone, then you probably have a tumor that's overproducing hormone.
Scott LuperHOST
21:50
That's called Cushing's disease.
Scott LuperHOST
21:52
There's other diseases that are associated with this as well, but the test is good for that.
Scott LuperHOST
21:56
And also, if you're not making any hormone whatsoever, it's called Addison's disease, and the test is good for that.
Scott LuperHOST
22:01
But Addison's is zero, Cushing's is 100, and there's lots of stuff in
Haley FieldsHOST
22:04
between.
Scott LuperHOST
22:05
There's another 99, right? States of being, and it doesn't really, it's not good for testing any of the one of those, except for in a very crude fashion.

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