Cochrane Library
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Search complete. 12 mentions across 12 episodes found for "Cochrane Library".
Oct 13, 2026
Trevor BachmeyerHOST
In heart failure, carnitine is depleted.
Trevor BachmeyerHOST
So 2013, Cochrane Database of Systemic Reviews showed L-carnitine supplementation improves cardiac function, reduced mortality rate in heart failure patients 27%.
Trevor BachmeyerHOST
That's a big number, you guys.
Trevor BachmeyerHOST
Please understand, I'm giving you these 'cause, 'cause I want you to understand this.
HannahGUEST
But there is a big sort of gold standard.
HannahGUEST
It's called the Cochrane Database.
HannahGUEST
So they have a big one on quantitative care with midwives.
HannahGUEST
And the obvious one is a lower chance of unnecessary interventions, so episiotomy rates, cesarean rates, instrumental birth rates, needing pain relief.
Jason YehGUEST
And then we're gonna add a placebo arm, which is like, "Oh, this is not even the drug.
Jason YehGUEST
This is, like, fake pills." And then all of a sudden the effect size disappears, and then 10, 15 years later, after millions of dollars has been spent, what we call a meta-analysis and, and there's, there's a, there's a series of them called the Cochrane Reviews in medicine.
Jason YehGUEST
That's basically as high up to capital T Truth, all caps, as you can get in our field.
Jason YehGUEST
If the Cochrane says it's true, that's about as true as we can believe.
Ken BerryHOST
That's your actual blood pressure reading, and I can almost guarantee you it's gonna be significantly lower than the number that your doctor got at his or her office.
Ken BerryHOST
Now, you may have heard of the Cochrane Library.
Ken BerryHOST
They do, uh, systematic analyses of all the different studies, and they come up with rational commonsense answers to questions.
Ken BerryHOST
And in 2020, they put out their latest blood pressure systematic review, and they said 140 over 90 or l- less than that, that's a normal blood pressure regardless of what the American Heart Association says.
Hector ChapaGUEST
[sighs] This was so impactful.
Hector ChapaGUEST
This became the Cochrane Database logo.
Hector ChapaGUEST
I love it.
Hector ChapaGUEST
I love it.
Rory SpiegelHOST
So how much of a benefit could it have? And so these authors thought to answer this question in large vessel ischemic stroke that would benefit from a thrombectomy.
Rory SpiegelHOST
And so they conducted a PubMed search, Web of Science, Cochrane Library, et cetera, et cetera, looking for studies with radiologically confirmed large vessel inclusion who underwent mechanical thrombectomy and comparing direct transport to comprehensive center with initial evaluation at the local center followed by transfer.
Rory SpiegelHOST
And they included randomized control trial, cohort studies, and case control studies, though almost all the studies were cohort
Ryan RadeckiHOST
studies with one secondary analysis of a randomized control trial.
Kirk ParsleyGUEST
But what I did is I said, "Well, let's just work on normal brain physiology." And to your point, tryptophan is like this huge hinge pin, and that was the first thing I looked up, like, h- does tryptophan help with sleep and why? 'Cause I knew you could buy tryptophan at a, at, you know, at a vitamins shop, so maybe that'll help.
Kirk ParsleyGUEST
So I s- I went to things like Cochrane Database, Google Scholar, you know, PubMed, just normal, traditional things, what, you know, and said, looked up what, what supplements help with sleep and why.
Kirk ParsleyGUEST
And so then I, you know, this is part of my education and learning about physiology and what, and what normally happens.
Kirk ParsleyGUEST
So the reason tryptophan has any effect on you, um, so tryptophan's just an amino acid that's in meat.
Mirela CernaianuHOST
This review was performed to study the efficacy and safety of PRP in women suffering from female sexual dysfunction and stress urinary incontinence, either or, and to explore the optimal dosing frequency and area of injections or the duration of treatment.
Mirela CernaianuHOST
So they performed a systematic search on PubMed, Embase, and the Cochrane Library database up to January of 2023.
Mirela CernaianuHOST
They found four prospective and one retrospective study that explored female sexual dysfunction.
Mirela CernaianuHOST
A total of 327 women with a mean age of 51 plus minus 12 years were included in these studies.
SineadHOST
Yeah
CharlesHOST
... is the, there's, there's this thing called the Cochrane Library-
SineadHOST
Mm-hmm
CharlesHOST
...
BrewHOST
There's been more research on this topic in recent years too.
BrewHOST
A meta-analysis of data taken from the Chinese Medical Reference Database, Medline, and Cochrane Library compared the IQs of children born in areas of varying iodine sufficiency in China.
BrewHOST
Over 12,000 children were included in these studies and found that those living in iodine-sufficient areas had, on average, IQs 9.85 points higher than those living in iodine-deficient areas without supplementation.
speaker_3VOICE_ACTOR
So is iodine actually making people smart then? Was I right, huh?
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