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Chronotropic
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MENTIONS
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EPISODES
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PODCASTS
Search complete. 2 mentions across 2 episodes found for "Chronotropic".
Sep 10, 2026
#318 Norepinephrine Masterclass: Foundations, Clinical Scenarios, Dosing, Bedside Applications
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25:42speaker_0HOST
Now, norepinephrine does have some beta-1 effects.
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25:44speaker_0HOST
Remember we said beta-1 receptors are on the heart, and that can mildly increase contractility and mildly increase heart rate, cause the heart to squeeze harder and cause it to beat faster, right? Chronotropic support, right? And inotropic support.
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26:00speaker_0HOST
So chronotropic support is heart rate.
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26:02speaker_0HOST
Inotropic support is contractility.
#317 Dobutamine vs Milrinone Masterclass: Mechanisms, Hemodynamics, Dosing, And Clinical Use
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3:27speaker_1HOST
Heart rate increases are known as chronotropy.
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3:29speaker_1HOST
So inotropy is contractility.
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3:33speaker_1HOST
Chronotropy is heart rate.
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3:37speaker_1HOST
So beta-1 receptor agonism stimulating beta-1 receptors in the heart, dobutamine increases myocardial contractility, also known as inotropy, and it increases heart rate, also known as chronotropy, although the primary effect is this increase on myocardial contractility.
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3:52speaker_1HOST
Dobiumine does have some slight beta-2 adrenergic effects.