
Child–Pugh score
3
MENTIONS
3
EPISODES
3
PODCASTS
Search complete. 3 mentions across 3 episodes found for "Child–Pugh score".
Oct 13, 2026
Ghassan Abou-Alfa, MD, JD, MBA, PhD(hc) - Redefining Therapeutic Progress in HCC: Extending the Benefits of Immunotherapy to Earlier Stages of Disease
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18:08Ghassan Abou-AlfaGUEST
So back to our patients.
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18:09Ghassan Abou-AlfaGUEST
Remember our lady, forty-five-year-old with hepatitis B, with abdominal pain and BCLC B, Child-Pugh A, good performance status, bilobar disease with largest lesion six centimeter, and no macrovascular invasion.
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18:22Ghassan Abou-AlfaGUEST
Well, what would be your treatment choice? TAILOR alone? PD-1/PD-L1 inhibitor alone? TAILOR plus PD-1/PD-L1 inhibitor? Or TAILOR anti-TKI? I think already I showed you a little bit of suggestion regard to the TAILOR plus the PD-1/PD-L1, and we add on the tremelimumab if it's available.
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18:45Ghassan Abou-AlfaGUEST
And if anything, the patient, uh, was of course, uh, debriefed on the value of the TAILOR.
Ghassan Abou-Alfa, MD, JD, MBA, PhD(hc) - Redefining Therapeutic Progress in HCC: Extending the Benefits of Immunotherapy to Earlier Stages of Disease
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18:08Ghassan Abou-AlfaHOST
So back to our patients.
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18:09Ghassan Abou-AlfaHOST
Remember our lady, forty-five-year-old with hepatitis B, with abdominal pain and BCLC B, Child-Pugh A, good performance status, bilobular disease with largest lesion six centimeter, and no macrovascular invasion? Well, what will be your treatment choice? TACE alone? PD1/PDL1 inhibitor alone? TACE plus PD1/PDL1 inhibitor? Or TACE anti-TKI? I think already I showed you a little bit of suggestion regard to the TACE plus the PD1/PDL1, and we add on the tremelimumab if it's available.
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18:45Ghassan Abou-AlfaHOST
And if anything, the patient, uh, was of course, uh, debriefed on the value of the TACE, and if anything, uh, so, uh, uh, would you consider like something along the EMERALD-1? Guess what? If anything, the patient EMERALD-3 was an appropriate opportunity for her to join in, theorize th-- we theorized that.
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19:06Ghassan Abou-AlfaHOST
And if anything, the patient was on the Strate plus TACE regimen on B, and if anything, she only developed a hypothyroidism after three or point five months on therapy.
#150 PP: CLD
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9:06Sam WilliamsHOST
And in portal hypertensive ascites, I would expect a high gradient, which would be a value of at least 1.1 grams per deciliter.
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9:18Sam WilliamsHOST
And how would you assess the severity of his liver disease? So I could calculate a prognostic score such as the Child-Pugh score or a MELD score where this was appropriate.
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9:32Sam WilliamsHOST
And I could also assess for complications with imaging, as I've described, and consider upper GI endoscopy for varices.
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9:41Sam WilliamsHOST
And I could also consider calculating a FIB-4 score to estimate the degree of liver fibrosis present in this patient.