UA Local 502 (United Association of Plumbers, Pipefitters & Service Technicians Local Union No. 502)

Yeah.

The one published in Cell Reports.

Yeah.

And it just it completely flicks the script on how metabolic dysfunction actually happens.

They reach for high-fat, highly processed comfort foods to just get through the day.

Right.

So how did the Cell Reports study actually isolate the timing of the hormone from the junk food people usually eat when they're stressed?

Well, they ran a beautifully controlled four-part experiment to separate those exact variables.

You said three mechanisms.

The second one came out of a 2024 study in Cell Reports, El-Grawani and colleagues.

They were working with sleep-deprived mice and they found that a specific circuit within the lateral prefrontal cortex becomes functionally impaired under sleep deprivation.

But the crucial finding was that this impairment could be dissociated from sleep pressure itself.

Scientists have discovered that some centenarians may host rare cancer-killing cells.

The findings, published in the journal Cell Reports, claims this rare type of immune cell starts expanding and cloning itself in people who live past a hundred, which they say could be helping preserve their longevity by killing cancers before they grow.

The cells are CD4 cytotoxic T lymphocytes, which are already known to kill some cancers, and they appear to be more common in humans above the age of a hundred.

To better understand them, the authors analyzed the blood of twenty-eight people aged either seventy to ninety-nine, one hundred to a hundred and nine, or over a hundred and ten.

Now, I think our question is not if it has an effect or not, but how to apply this in a big scale.

Erika Santoro is based at King Abdullah University of Science and Technology, and the results of her experiments were just shared in the journal Cell Reports.

We're continuing with a tone of optimism here on Inside Science with the book Despite It All, a handbook for climate hopefuls.

With the UN Environment Programme declaring that the idea of limiting global warming to 1.5 degrees is now a busted flush and CO2 being pumped into the atmosphere as fast as ever, maybe we need to think about what progress the human race has made in protecting the planet.

If you were never a baby, I would like to know how that possibly happened.

Um, researchers just published an open access paper in Cell Reports on what they call retrosplenial cortex maturation aligns with the transition from infant forgetting to persistent memory.

What does this mean? Well, what this means is that...

I'm gonna put a picture up on the screen right now.

So we utilized that resource.

We w-- came here, we said, "Okay, let's just go focus deeply, take as unbiased approach as we can, and see where things go wrong in early melanoma initiation." And that's the first paper we published in Cell Reports with, you know, um, Fizzi et al., if you will look.

And that is where we, we sort of understood that, okay, there are a lot of differences occur in, uh, changes in, um, in enhancer states.

And again, the field was evolving at that point, and we saw a lot of enhancers, you know, being important in cancer, which again, to date, is still those true, and we have a lot of work that is still unpublished in that area.

Um, Ron's lab was next door, and Ron made a lot of mouse models, so did we in Linda's lab.

So we start-- we made a mouse model, [chuckles] and we looked at what, what happens.

And, and it turned out that the mouse model really showed very drastic phenotypes, which is what we published in the Cell Reports paper in 2010.

At the same time, when we moved to MD Anderson, there was another group, Mingyu Li's group, who was actually studying KMT2D.

Scientists have yet to fully turn the comic book gift from fiction to fact, but virtual reality is offering hints of what it's like to learn to fly.

After training to use virtual wings, people's brains responded to wing images more similarly to how they respond to images of arms, making wings seem more like body parts, cognitive neuroscientist Yanxia B and colleagues report." And this study was published in a journal called Cell Reports.

I love that there's something out there called Cell Reports.

[laughs] And, uh, this, uh, scientist then goes on to talk about how plastic the brain really is, which I thought was great 'cause last week our guest, Andrea Hairston, she spoke quite a bit about plastic brains in her work.

Indeed.

Uh, the answer to this enigma could be gut microbiota, and today we know that, uh, gut microbiota, uh, can produce and release of thousands of chemical compounds, uh, toward the host, which are circulating in the bloodstream and reach out, uh, blood vessels.

Um, in this project, uh, which is partly published in Nature Aging and another follow-up study, uh, is currently under revision Cell Reports.

Uh, keep fingers crossed for that [laughs].

Uh, in, in, in this, uh, project, we identified, um, as you indicated, um, microbial metabolite phenylacetic acid, uh, and its derivative, uh, PAL and phenylacetylglutamine, uh, increase with age and atherosclerosis.