CD31

I've definitely seen some literature saying that some, you know, certain liver specific promoters can express in LSX and possibly even in cut for cells as well.

And I believe you talk about you mentioned you did see some LSX that were some CD31 positive

GFP

positive

So CD31, just a marker for the blood vessel, right? The clostridium differentiation protein and surface.

That's what I'm talking about.

You understand the density, that means the amount of GAM cells, remember, glioma-associated macrophages, with CD31-positive blood vessels.

when they see them with the reduced within the glioma and the TREM2 deficient mice in the male, that means that there is a communication that's being affected by TREM2 that deals with blood circulation.

What's coming in the blood? Well, nutrients and oxygen.

And I'll give you a little more detail, it doesn't act alone.

CD38 has to interact with another protein which actually is a ligand activator of CD38, and that's CD31.

So what is CD31? Well, it has a couple of other names like most proteins do, because when they were first examined, they pick up a local common name.

So CD31 in the literature used to be called PCAM1.

I remember when it came in the literature.

PCAM stands for platelet endothelial cell adhesion molecule one.

Yeah, CD31 is an adhesion.

So that protein, CD31, is a 130 kilodalton type one transmembrane glycoprotein.