Caspase 3

Yeah, this biochemical shift physically injures the mitochondria inside the neurons.

And the damaged mitochondria then release cytochrome C, which activates a specific enzyme called caspase-3.

Caspase-3?

Yes.

Think of caspase-3 as the primary executioner enzyme of the cell.

Once it's activated, it systematically dismantles the neuron from the inside out.

That sounds terrifying.

But this pathophysiological understanding is aggressively driving the search for neuroprotective adjuncts.