Cardiovascular–kidney–metabolic syndrome
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Search complete. 16 mentions across 4 episodes found for "Cardiovascular–kidney–metabolic syndrome".
Oct 19, 2026
Chiadi NdumeleGUEST
I have recently just been the chair of the Council on Lifestyle and Cardiometabolic Health for the American Heart Association.
Chiadi NdumeleGUEST
And I've had the great privilege of chairing the American Heart Association and American College of Cardiology's work on the CKM Syndrome Initiative, including the presidential advisory and scientific statement that introduced this concept in 2023, and then the most recent AHA, ACC, ADA, ASN clinical practice guidelines around CKM Syndrome that came out just in June of 2026.
Chiadi NdumeleGUEST
So it's great to have the chance to talk with you today.
Nicholas PenningsHOST
And it's great to talk with you today too.
Chiadi NdumeleGUEST
So metabolic factors.
Chiadi NdumeleGUEST
kidney factors and cardiovascular disease.
Chiadi NdumeleGUEST
It's a progressive condition that's reflected by the stages of CKM syndrome and it's associated with a greater likelihood of earlier cardiovascular disease and most notably premature mortality.
Chiadi NdumeleGUEST
The cardiovascular kidney metabolic construct is meant to reflect the fact that these factors are not isolated conditions despite that that's how we often treat them in clinical practice.
speaker_0HOST
Today, we're joined by Dr. Salvatore Viscomi, CEO and co-founder of Karner Health.
speaker_0HOST
KANA is an AI-driven platform built to detect, manage, and prevent Cardio Kidney Metabolic Syndrome.
speaker_0HOST
In just the past year, they've secured funding, landed a spot on Fortune's Most Innovative Companies list, and launched pilots reaching 35,000 people in Cameroon.
speaker_0HOST
Now they're expanding into the Democratic Republic of Congo and Southeast Asia, with a US launch on the horizon.
Karen LarmerHOST
If this patient were sitting in your exam room, how would you respond to the patient's statement? [upbeat music] The answer is C, and that distinction is the reason CKM syndrome matters.
Karen LarmerHOST
The twenty twenty-six AHA/ACC/ADA/ASN CKM Syndrome Guideline gives us a framework for looking at adults with risk factors before they arrive with heart failure, myocardial infarction, stroke, or another cardiovascular event.
Karen LarmerHOST
The goal isn't simply to give another name to a collection of risk factors.
Karen LarmerHOST
The goal is to recognize the trajectory early enough that we can change it.
LenaHOST
Then, a new FDA label in childhood nephrotic syndrome.
LenaHOST
Then, a cardiometabolic block, what nephrology's job is in CKM, atherosclerosis in CKD, how to actually get GLP-1s going in CKD clinic, and that dipstick adherence study.
LenaHOST
We close on AI, where it can save time in a nephrology practice, and how to train fellows so it doesn't hollow them out.
MarcusHOST
Let's go.
11 MINS LATER
MarcusHOST
Yet referral guidance says refer below an eGFR of thirty, and practice reads that as refer at thirty, ignoring proteinuria, an abnormal sediment, or an unclear cause.
MarcusHOST
And patients first seen at stage four or five progress faster and crash start more.
LenaHOST
They're also frank critics of CKM itself.
LenaHOST
Albuminuria is optional in it.