
bullous pemphigoid
DiseaseWikipedia
1
MENTIONS
1
EPISODES
1
PODCASTS
Search complete. 1 mention across 1 episode found for "bullous pemphigoid".
Sep 28, 2026
Ep 010. Psoriasis Part 1: Pathophysiology, Clinical Features, and Variants
J
7:53Jonny HatchHOST
No, exactly.
J
7:54Jonny HatchHOST
When I think about autoimmune diseases as well as inflammatory conditions, I like to separate them because when I think about autoimmune conditions, I think about autoantibodies against some sort of Self-antigen, right? So like if you think about bolus pemphigoid, there's autoantibodies against BP-180, BP-230, and that's causing this blistering.
J
8:19Jonny HatchHOST
I think about hyperinflammatory conditions or inflammatory conditions like psoriasis, where you have an increase of the cytokines like IL-17, IL-23, these sort of things that are causing just increased inflammation, but there's no real antibody against a self-antigen.
J
8:35Jonny HatchHOST
So oftentimes we talk about psoriasis, we talk about it being more hyperinflammatory condition rather than a true autoimmune condition.