But how do over-the-counter medications contribute to polypharmacy? And what are the cautions that we should be thinking about with over-the-counter

items? So over-the-counter medications can be bought in the store or online without a prescription.

And the most common one that we see is oral NSAIDs, such as ibuprofen, Motrin, Advil, Aleve, Naproxen.

Long-term use of these medications can lead to leg swelling.

Blood pressure increasing, gut bleeding, kidney damage, and tinnitus, which is ringing in the ears.

And if you happen to be taking any blood thinners, in addition, this really magnifies your risk of bleeding through the gut.

Another class of anticholinergic agents you can get over the counter is for sleep, diphenhydramine, doxylamine, Benadryl, the PM medications, Tylenol, PM, ibuprofen, PM, as we discussed, impair cognition, vision, bladder, bowel imbalance.

And you've already shared several great patient stories, but can you think of any success story that really jumps out at you that you think about from time to time where deprescribing made a very meaningful difference to their quality of life? I had