bone marrow

fast, man.

And this year I didn't do any bone marrow, though.

Like, usually I'll drizzle bone marrow on it.

I want to try bone marrow.

Oh, it's amazing.

Like, it's amazing.

That thing was fucking starting grease fire.

I was not happy.

He discusses MYB activity drives emergent enhancer activation and enhancer promoter interactions in acute lymphoblastic leukemia with Dr. Thomas Milne.

He also talks with Dr. Dominique Bonnet about her article entitled, Remodeling of the Bone Marrow Vasculature Induced by Venetoclax and Azacitidine Damage.

Hello, everybody.

My name is James Griffin.

Good luck with the future studies of MIB.

This is clearly a key factor in ALL and AML, as you point out.

We're going to go on to the second paper, which is entitled Remodeling of the Bone Marrow Vasculature Induced by Venetoclax and Azacitidine Damage.

And this is going to be discussed by Dr. Dominique Bonnet from the Hematopoietic Stem Cell Laboratory at the Francis Crick Institute in London.

So what happens, we're going to learn details about the kulis.

Remember, there are certain bones that they are sealed, like a thigh bone, but they're filled with marrow.

Marrow, to begin with, has a din of basa.

Dam nevela.

Remember this, guys.

The heart is the house of guard, in which all the veins meet; and through them reason sends her commands to the extremity of her kingdom.

When the passions are in revolt or danger approaches from without, then the heart beats and swells; and the creating powers knowing this implanted in the body the soft and bloodless substance of the lung having a porous and springy nature like a sponge and being kept cool by drink and air which enters through the trachea The part of the soul which desires meat and drink was placed between the midriff and navel where they made a sort of manger and here they bound it down like a wild animal away from the council chamber and leaving the better principle undisturbed to advise quietly for the good of the whole For the Creator knew that the belly would not listen to Reason and was under the power of idols and fancies Wherefore he framed the liver to connect with the lower nature contriving that it should be compact and bright and sweet and also bitter and smooth In order that the power of thought which originates in the mind might there be reflected Terrifying the Belly with elements of bitterness and gall in a suffusion of bilious colours when the Liver is contracted and causing pain and misery by twisting out of its place the lobe and closing up the vessels and gates And the converse happens when some gentle inspiration coming from Intelligence mirrors the opposite Fancies giving rest and sweetness and freedom and at night moderation and peace accompanied with prophetic insight when Reason and Sense are asleep For the authors of our Being in obedience to their Father’s will and in order to make Men as good as they could Gave to the Liver the Power of Divination Which is never active when Men are awake or in health But when they are under the influence of some disorder or enthusiasm Then they receive intimations which have to be interpreted By others who are called Prophets but should rather Be called Interpreters of Prophecy After Death these Intimations become unintelligible The Spleen which is situated in the neighbourhood on the left side Keeps the Liver bright and clean As a napkin does a mirror And the evacuations of the Liver Are received into it And being a hollow tissue It is for a time swollen With these impurities But when the Body is purged It returns to its natural size The truth concerning the Soul can only be established by the word of God Still we may venture to assert what is probable both concerning Soul and Body The creative Powers were aware Of our tendency to excess And so when They made the belly To be a receptacle for food In order that Man Might not perish by insatiable gluttony They formed the convolutions of the intestines In this way retarding the passage of Food through the Body Lest Mankind Should be absorbed in eating and drinking And the whole race Become impervious to Divine Philosophy The creation of bones and flesh Was on this wise—The foundation of these Is the Marrow which binds together Body and Soul And the Marrow is made Out of such of the primary triangles As are adapted by Their perfection To produce All the four Elements These God took And mingle Them in due proportion Making as many kinds of marrow As There were hereafter To be Kinds of Souls The receptacle of the divine soul He made round and Called That portion of the Marrow Brain intending that the vessel containing This Substance should be the Head The remaining Part He Divided Into long and Round figures And to these as to anchors fastening the Mortal Soul He proceeded to Make the Rest of the Body First forming for Both Parts A covering of Bone The bone was Formed by sifting pure Smooth earth and wetting it with marrow It was then thrust alternately into fire and water and thus rendered insoluble by either Of bone he Made a globe which he Placed around the brain Leaving a Narrow opening And Around the marrow of the Neck and Spine he formed the vertebrae Like hinges Which extended From the Head Through the Whole of the trunk And as the bone was brittle and liable to mortify and destroy The Marrow by too great rigidity and susceptibility to heat and cold He contrived sinews and Flesh The first to give flexibility the second to guard against heat and cold, and to be a protection against falls containing a warm moisture which in summer exudes and cools the body, and in winter is a defence against cold.

Having this in view, the Creator mingled earth with fire and water, and mixed with them a ferment of acid and salt so as to form pulpy flesh but the sinews he made of a mixture of bone and unfermented flesh giving them a mean nature between the two and a yellow colour hence they were more gluttonous than flesh but softer than bone The bones Which have most of the living soul within them He covered With the thinnest film Of flesh Those which Have least of it He lodged deeper At the joints He diminished the Flesh In order not To impede The flexure Of the limbs And also to avoid Clogging the Perceptions Of the mind About the thighs And arms Which have No sense Because there Is little Soul In the marrow And about The inner Bones He laid The flesh Thicker For where The flesh Is thicker There is Less feeling Except In certain Parts Which the creator Has made Solely Of flesh As for example The tongue Had the combination Of solid Bone and Thick flesh Been consistent With acute perceptions The creator Would have Given man A sinewy And fleshy Head And then He would have Lived twice As long But our creators Were of Opinion That a shorter Life which was Better Was preferable To a longer Which was Worse And therefore They covered The head With thin Bone And placed The sinews At the extremity Of the head Round the neck And fastened The jawbones To them Below the face And they Framed the mouth Having teeth And tongue And lips With a view To the necessary And the good For food Is a necessity And the river Of speech Is the best Of rivers Still the head Could not Be left A bare globe Of bone On account Of the extremes Of heat And cold Nor be allowed To become Dull and Senseless By an overgrowth Of flesh Wherefore It was Covered by a peel Or skin Which mat And grew By the help Of the cerebral Humour The diversity Of the sutures Was caused By the struggle Of the food Against the courses Of the soul Skin of the head Was pierced By fire And out of the punctures Came forth A moisture Part liquid And part Of a skinny Nature Which was Hardened by the pressure Of the external Cold And became Hair And God Gave hair To the head Of men To be a light Covering So that it might Not interfere With his Perceptions Nails were Formed by Combining Sinew Skin and Bone And were Made by the Creators With a view To the future When as they knew Women and Other animals Who would Require Them Would be framed Out of Men The gods Also mingled Natures Akin to that Of men With other Forms and Perceptions Thus trees And plants Were created Which were Originally Wild And have been Adapted By cultivation To our use They partake Of that third Kind of life Which is Seated Between the Midriff And the navel And is altogether Passive And incapable Of reflection When the Creators had Furnished all These natures For our Sustenance They cut Channels through Our bodies As in a garden Watering them With a perennial Stream Two were Cut down The back Along the Backbone Where the Skin and Flash meet One on the Right and the Other on the Left having the Marrow of Generation Between them In the next Place they Divided The veins About the Head and Interlaced Them with Each other In order That they Might form An additional Link between The head And the Body and That the sensations From both Sides might Be diffused Throughout the body In the Third place They contrived The passage Of liquids Which may Be explained In this way Finer Bodies retain Coarser but Not the coarser The finer And the Belly is capable Of retaining Food but Not fire And air god Therefore formed A network Of fire and Air to irrigate The veins having Within it two Lesser nets and Stretched cords Reaching from Both the lesser Nets to the Extremity of the Outer net the Inner parts Of the neck Were made by Him of Fire the Lesser necks and Their cavities Of air the true Ladder he made To pass into The mouth the one Ascending by The air pipes From the lungs The other by The side of the Airpipes from The belly the Entrance to the First he divided Into two parts Both of which He made to Meet at the channels Of the nose That when the Mouth was closed The passage Connected with It might still Be fed with Air the cavity Of the network He spread around The hollows Of the body making the entire receptacle to flow into and out of the lesser nets and the lesser nets into and out of it while the outer net found a way into and out of the pores of the body and the internal heat followed the air to and fro these as we affirm are the phenomena of respiration and all this process takes place in order that the body may be watered and cooled and nourished and the meat and drink digested and liquefied and carried into the veins The causes of respiration have now to be considered.

The exhalation of the breath through the mouth and nostrils displaces the external air, and at the same time leaves a vacuum into which, through the pores, the air which is displaced enters.

Also the vacuum which is made when the air is exhaled, through the pores is filled up by the inhalation of breath through the mouth and nostrils.

No, no. God's sake, man.

That's my risotto at Melanesia with roasted bone marrow.

Oh, did I go wrong? You

tasted fish.

Then, you know, again, like everything in Italy, if you go to Venice, they will say, then this is... not alonda enough if you go to calabria they'll say oh that's but this was a

particular dish that your grandmother used to cook which was the risotto milanese

risotto she wouldn't serve it all the time with uh bone marrow but you know the risotto with saffron was a thing and the best thing about is then she will make always quite a lot of it so then the day after the one kept in the fridge, then she would place it down and make a risotto al salto.

And that was the favorite thing that me and my brother used to have.