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Bifidobacterium longum

Bifidobacterium longum

BacteriaWikipedia

Search complete. 10 mentions across 4 episodes found for "Bifidobacterium longum".

Aug 29, 2026

Michael SchmidtHOST
23:17
So how does Bifidobacterium manage to adapt so quickly without waiting for millions of years for point mutations to accumulate so that that DNA can actually impact on the fitness of the microbe and us ultimately as the host? Now, today's paper starts with a fundamental conundrum in human gut ecology.
Michael SchmidtHOST
23:42
Bifidobacterium species, like the one they're gonna work on, Bifidobacterium pseudocatalanum and Bifidobacterium longum and breve, are all absolute workhorses in our dig- digestive tract, especially when we're newborns, infants, and that's effectively where all the data come from.
Michael SchmidtHOST
24:05
These are stool samples that they collected from 12 inf- infants longitudinally.
Michael SchmidtHOST
24:12
So when we eat a meal rich in complex plant polysaccharides, oligosaccharides, or even human milk as these infants do, um, these are the bacteria responsible for fermenting those non-digestible carbohydrates into short-chain fatty acids like acetate and lactate, which then serve to nur- nourish our colonocytes.
Kiran KrishnanGUEST
27:15
I'll give you an example that's really, really very glaring and clear.
Kiran KrishnanGUEST
27:18
So there's a strain that we work with called Bifidobacterium longum.
Kiran KrishnanGUEST
27:23
1714, right? That 1714 denotes that specific subspecies of Bifidobacterium longum.
Kiran KrishnanGUEST
27:30
Now, there's tons of Bifidobacterium longums out there.
Kiran KrishnanGUEST
27:33
You'll see them in all kinds of probiotics.
Kiran KrishnanGUEST
27:35
But the 1714 strain has a particular gene that codes for other genes that make something called the exopolysaccharide.
Kiran KrishnanGUEST
27:44
The exopolysaccharide is this unique conformation of carbohydrates that are on the outside layer of the cell.
Kiran KrishnanGUEST
27:50
In fact, when you look at this particular bifidobacterium longum underneath the microscope, you see all these amazing tentacles coming out
Ragen McGowanGUEST
33:48
So it- in any case, when you're looking for a probiotic, find the one where there's research for that specific strain that's showing the efficacy that you're interested in.
Ragen McGowanGUEST
33:57
But specifically for pets, um, and their stress response or anxious behavior, we were targeting a pathway which we could tap into with this, uh, Bifidobacterium longum BL999.
Ragen McGowanGUEST
34:10
Uh, we set up a really holistic approach again, where we were doing, uh, behavioral measures and physiological measures-
Ira PastorHOST
34:17
Mm-hmm
Oscar CoetzeeGUEST
17:16
But the, the, the most incredible thing about Akkermansia is the fact that it literally helps us to produce more of our own cells, right? Like, I mean, it's literally rejuvenates, rejuvenating some of our intestinal cells.
Oscar CoetzeeGUEST
17:29
Now, the other two that we haven't mentioned completely yet would be Bifidobacterium longum.
Oscar CoetzeeGUEST
17:34
Lots of research on mental health, as you know.
Oscar CoetzeeGUEST
17:36
And then Bifidobacterium adolescentis.

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