That's great.

I think one big change that we've seen t- over the past few years really is that there's more and more infrastructure to do this collaboratively and at scale that didn't exist when, you know, Pat and I were starting our research careers.

Um, so Pat and I are both members of the Cliff Consortium, which is a multicenter, uh, effort to standardize ICU data so that it can be used for studies acr- uh, across centers for, uh, whether it's sort of in-depth analyses of ventilator physiology or delivery science.

And, you know, that required a collaborative effort of multiple sites to bring-- to, to come together and agree on what data elements actually need to be included in these studies, but it's now enabling team science across the country and actually really centers even outside the US.

And on the biological scale, it's-- on the biological side, it's possible to do biology on scale, multiple modality work.

Uh, there's-- Our new lenses in our complex patients that we didn't have available even a few years ago, and we're starting to see the fruits of that work.

But I think, um, uh, both in, in the line of, of what we talked about earlier, which is, uh, data science and thinking about, you know, variation in both care delivery and variation in patient presentations.

And, you know, from our group at UCSF, um, I think you touched on a really important point, which is that crossing silos, crossing disciplines, like is really important in our patient population.