Aqueous humour

Usually we look at gene expression to detect DNA and mRNA proteins that are expressed, but really what's important is maybe the proteins expressed.

And so they go through the history of using either blood-based proteomics for metastasis or now aqueous humor proteomics to get more information in a less invasive manner about tumors and especially how that may relate to uveal melanoma.

And there's the idea that there may be diagnostic potential with aqueous.

They've talked about a few studies we can discuss where they talk about GP status.

So Mara, I'll talk with you.

I'll ask you first.

So proteomics, we'll get to retinoblastoma a little later because I know that there's been some studies looking at that, which Jesse Berry had published a few years ago at Aqueous Humor retinoblastoma i've heard less as a retina doctor about this related to uv melanoma so this is interesting for me to read what were your takeaways from this concept and how realistic is this in the near future that this would be a viable let's say replacement for biopsy in cases where you want to get prognosis

Yeah, no, that's an excellent question, Jay.