APAF1
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Search complete. 1 mention across 1 episode found for "APAF1".
Oct 17, 2026
speaker_2HOST
He sure did.
speaker_1HOST
He carried a nonsense mutation in the APAF1 gene on chromosome 5.
speaker_2HOST
Right.
speaker_1HOST
A nonsense mutation basically creates a premature stop signal in the gene, completely halting the production of a crucial protein.