So

the truth is we have a lot that we don't know about this.

To be clear, though, especially for those who don't.

We're brave enough to admit that, right? Exactly.

But, you know, just I know there's a lot of uncertainty about even what the term allergy means.

So what it's not for sure is an IgE reaction to the NSAID.

So it's not like a bee sting or peanut where, you know, we have an antibody that's binding to the drug itself.

But I think in terms of outlining what exactly an in-office challenge is, what are the safety parameters of it? How do you do it in these suspected AERD patients so that if you do provoke an AERD reaction, it's done safely? Can you walk us through in your clinic specifically, your specialty clinic, how do you guys set up aspirin challenges?

And I just wondered, is it because they haven't got the skills to do it, which I think is probably partly true, or that the audience wouldn't quite take it?

Interesting.

I think it's a mix of of both those things and something else.

So definitely there is a skill element.

And like, you know, you see new comedians do like shock humor for the sake of it.

There's not skill behind it.

So there's an element of like, oh, well, sex is funny and crude and just saying it will be fine.

I mean, uh, I mean, you may as well tell us what the show is.

Yes

... intens- intensified my attraction to people.

But yeah, when I was nine or 10 I, I met, met my friend, and I was r- like very obsessed with them in a f- friend way, and then maybe later, post Bugs Malone, I was like, "Oh, actually, maybe there's, there's more to this obsession." But I think that's, that's really common with gay people to mix up and, like, cross wires with platonic, romantic, and sexual attraction because, like, there's not framework existing around you.

So you're like, "Oh, I feel really close to this person.

It must be love." And it's like, oh, no, they're just a friend.

But you're just figuring it out.

So I definitely had a lot of mistakes like that.

Mm-hmm.

Now look at you.

So, [sighs] um, started just kind of observing.

I-- y- you can ask my wife, I observe way too much.

Um, but I noticed a lot of things, and I started listening to parents that, you know, were telling us about, you know, things that were kind of a, a struggle for them when they, when they were coming to drop their kids off.

And so I just started giving feedback t- to Tyler through, uh, you know, th- with that, and started making some changes for safety purposes and all that.

And I guess throughout that somewhere, Tyler said, "Hey, I want you to head up the parking team and, and kinda lead that, that charge." So, um, that's, that's what I do.

I've, I've been a part of, actually, um, in his small group-

[audience applauds]

And would you describe yourself? as more comfortable or confident? And you can be contextual.

Oh, that's a good question.

See, my definition of confidence is understanding your flaws, but still holding yourself in high regard.

And it took me a long point to get to that point.

And I always used to very much doubt myself, imposter.

But that was internal, right? But outside in the world.

And I think, again, that's probably why I went through that workplace bullying scenario is because I've come out very confident, very loud.

Yeah.

I still do go back and talk about life

in the West Country, as it were, but obviously I've got a fresh life and I've lived in London for a couple of years before as well, so...

Yeah, lots has changed, and I've just got more life experience and world-weariness to call on.

Obviously, yeah, having more life experiences is amazing for increasing your pool of material.

But actually, as well as having more venues, having more varied audiences has been very useful.

I think growing up in the Southwest was a great comedy training ground because it was a very varied, you know, be with students in Bristol or you can be at a meat raffle in the back room of a pub in Cornwall and you have to play to all those audiences.

So, yeah, I think it makes you a very... sort of multi-hyphenate performer.

I know it's a cliche, but it is true, isn't it? Because laughter is very near to crying, isn't it, on the spectrum? So without obviously spoiling your set, what sort of things do you go into? Is it grief because you've lost a loved one or is it mental health or what kind of things will chime with the audience?

guess we wanted to see with the the rest of this research whether the challenges are truly challenges or whether they're still the brands that have maximized their brand fame and this is where that two by two grid comes in right because we could track the mental availability versus algorithmic availability and see whether it's the same brands that the brand fame and mentally available now obviously we can't see the graphs that we've created like i said you have to go to the website to see that But we can at least talk about the four segments that we discovered in this research, right? So could you talk through each of those four and how we kind of grouped the different brands against mental and algorithmic availability?

Yeah, exactly.

So as I mentioned, there's a quadrant and then you've got in the top right-hand corner, you've got those that are ranked highly on both.

We call these the titans.

So these are brands that are dominant in the market.

They're well known by people.

They're well known by the LLMs, which means that they're going to be the top of the list for many people.

So if someone is looking to conduct a research campaign tomorrow, what would be your key tips to make sure that it's unique, impactful and

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Yeah, so I think we're kind of stuck with this industrial mode of working, which we, I say we, often people in Western Europe see as kind of natural as it were.

But in a sense, it's not natural.

The 40-hour week was arrived at through a series of negotiations between trade unions and the governments of the day and kind of factory owners in the 19th century.

So it just so happens that that's the figure we arrived at kind of 40 a 40 40 hour week um but before then um you know people would work a variety of hours you know if you're working in certain in agriculture for instance it might be the case that on on some occasions you'll be working around the clock certain seasons of the year other times you'll be working not very much so it's a kind of um your hours are attuned to the the task at hand as it were rather than saying well here's we have to fill in this 40 hours even if something only takes three hours for me to do this week i'm gonna have to drag it out for 40 40 hours so i i think that we need to start thinking a little bit about that that mode and you know people have started to talk about four-day working weeks and and stuff like that and and i think the reason i'm talking about this is because So this is something that on the left and the right, you know, there's almost kind of agreement on the left and the right that, you know, we should give people these kind of full-time jobs because it's worthwhile.

On the right, in the sense that, you know, it's a kind of negative thing in the sense that we don't want people to be lazy or we don't want them, as they would see it, taking money from the state.

But also on the left, and again, it's more positive, but it's a similar kind of idea that, you know, a job is worthwhile.

How do you contend these kind of, you know, admittedly not particularly robust arguments? Yeah.

We hope that we can connect these communities and that we can provide a starting point for this new era of AI and science to move forward.

So without further ado, let's get started on the first podcast.

We're really happy to have in the studio today, Andrew White, co-founder of Future House and newly formed start-up, Edison Scientific.

Um, rather than introduce him, I'll let him introduce himself.

Uh, hi, I'm Andrew from San Francisco, former professor, now running two start-ups: uh, one that's a nonprofit research lab and one that's a for-profit venture-backed company, and we're trying to automate science.

We're gonna get into all those points.

[chuckles] Yeah, really happy to be here.

Yeah.