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Amiodarone

Amiodarone

MedicationWikipedia

Search complete. 18 mentions across 10 episodes found for "Amiodarone".

Oct 28, 2026

Niraj SharmaHOST
8:33
Other medications such as flecainide are used if the heart is otherwise normal.
Niraj SharmaHOST
8:38
Amiodarone, for example, can affect the lungs, liver, and thyroid.
Niraj SharmaHOST
8:42
Your team will explain which checks you need.
Niraj SharmaHOST
8:45
If the heart muscle is weak, treatment for that weakness is also a key part of care.
Ken BerryHOST
9:46
They eat lots of sea vegetables and kelp, and all these things are very rich sources of iodine.
Ken BerryHOST
9:51
and so if as some people have said eating more than a milligram of iodine a day is very dangerous then the japanese should be extinct and indeed any other population of people who live near the ocean who get anywhere from 8 to 15 milligrams of iodine a day they should die if it's that terrible they should all have hyperthyroidism or autoimmune thyroiditis or whatever it is that this the expert says oh if you get too much iodine it will harm you Example number two, there's a medication called amiodarone that doctors like me give to patients who have heart failure or severe heart problems.
Ken BerryHOST
10:30
Amiodarone has 75 milligrams of iodine in it.
Ken BerryHOST
10:35
And most people take 200 milligrams of amiodarone either once or twice a day.
Ken BerryHOST
10:40
So that means the average person taking amiodarone is getting somewhere between 75 milligrams a day and 150 milligrams a day of iodine.
speaker_0NARRATOR
5:31
He pulled up the interaction checker, though he already knew.
speaker_0NARRATOR
5:34
Amiodarone inhibits the metabolism of warfarin.
speaker_0NARRATOR
5:38
The anticoagulant effect could double, triple.
speaker_0NARRATOR
5:41
Mr. Okafor could bleed into his brain by morning.

Unknown podcast

Cardiac Antiarrhythmic Drugs: Classification, Mechanisms, Effects and Side Effects

Oct 11 · 7 Mentions

A M ThirugnanamGUEST
5:33
Many drugs act on several channels.
A M ThirugnanamGUEST
5:37
Amiodarone, for example, has actions of all four classes, and it does not include newer targets.
A M ThirugnanamGUEST
5:45
So in 2018, an expanded modernized classification was proposed by Lai and colleagues.
A M ThirugnanamGUEST
5:54
It keeps the original four classes, subdivides them further, and adds new ones.

10 MINS LATER

Alexander WoodHOST
16:17
Class three: the potassium channel blockers.
Alexander WoodHOST
16:21
Let's start with amiodarone.
A M ThirugnanamGUEST
16:25
Amiodarone is the most effective antiarrhythmic drug we have and also one of the most toxic.
A M ThirugnanamGUEST
16:33
It is classified as Class 3 because it blocks potassium channels and prolongs repolarization and the QT interval.

Unknown podcast

Safe Cardiac Drug Selection During Pregnancy and Breastfeeding

Oct 11 · 3 Mentions

A M ThirugnanamGUEST
17:04
Catheter ablation, when needed for drug-refractory arrhythmias, should be performed in experienced centers with minimal or zero fluoroscopy, preferably in the second trimester.
SamanthaHOST
17:20
What about amiodarone? It's often used in cardiology.
A M ThirugnanamGUEST
17:26
Amiodarone should be avoided in pregnancy whenever possible and used only for life-threatening arrhythmias when other drugs have failed.
A M ThirugnanamGUEST
17:38
It contains a large amount of iodine and crosses the placenta, and it can cause fetal hypothyroidism, goiter, hyperthyroidism, growth restriction, bradycardia, QT prolongation, and possible neurodevelopmental effects.
A M ThirugnanamGUEST
17:56
Dronedarone is contraindicated in pregnancy.
A M ThirugnanamGUEST
17:59
If amiodarone is essential, for example, for recurrent ventricular tachycardia not controlled by other drugs before an ablation or defibrillator can be arranged, it can be used at the lowest effective dose and for the shortest time with monitoring of the mother's thyroid function And fetal growth and assessment of the newborn's thyroid function after birth.
A M ThirugnanamGUEST
18:27
Amiodarone also passes into breast milk in significant amounts, so breastfeeding is generally not recommended while taking it.
A M ThirugnanamGUEST
18:38
It's important to remember that in a pregnant woman with cardiac arrest, all standard resuscitation drugs, including amiodarone, should be given exactly as in non-pregnant patients, because saving the mother is the priority.

Unknown podcast

Congenital Heart Disease in Pregnancy: Diagnosis, Complications, Treatment, Food and Precautions

Oct 11 · 1 Mention

A M ThirugnanamGUEST
27:11
Endothelin receptor antagonists for pulmonary hypertension are teratogenic and must be stopped, while sildenafil and prostanoids can be continued.
A M ThirugnanamGUEST
27:23
Amiodarone is avoided where possible because of fetal thyroid effects.
A M ThirugnanamGUEST
27:29
Mineralocorticoid antagonists, especially spironolactone, are generally avoided.
A M ThirugnanamGUEST
27:36
Statins are usually stopped.

Unknown podcast

The Heart in Pregnancy: Physiological and Pathological Changes, Diagnosis, Complications and Treatment

Oct 11 · 1 Mention

A M ThirugnanamGUEST
28:46
Ventricular tachycardia in pregnancy should prompt a search for cardiomyopathy, including peripartum cardiomyopathy or inherited channelopathies like long QT syndrome, where beta blockers should be continued throughout pregnancy and particularly postpartum.
A M ThirugnanamGUEST
29:06
Amiodarone is avoided where possible because of fetal thyroid effects.
A M ThirugnanamGUEST
29:11
Implantable defibrillators can be continued, and catheter ablation, if needed, can be done with minimal or zero fluoroscopy techniques.
SamanthaHOST
29:22
What about aortic disease, such as Marfan syndrome?
Danielle CampagneHOST
17:27
Uh, you wanna get this patient ready for transport, and you also wanna get on the f- radio and get to your, contact your base hospital.
Danielle CampagneHOST
17:34
Um, and you may be directed or you can ask for orders for Amiodarone.
Danielle CampagneHOST
17:38
For us locally, we give 150 milligrams IV over about 10 minutes.
Danielle CampagneHOST
17:42
We repeat if needed according to our protocol.
RachelHOST
3:09
Class III antiarrhythmics work via potassium channel blockade.
RachelHOST
3:14
Amiodarone and sotilol prolong repolarisation by increasing the effective refractory period in phase 3 of the cardiac action potential.
RachelHOST
3:23
Class IV antiarrhythmics work as calcium antagonists or calcium channel blockers.
RachelHOST
3:29
Slowing of calcium influx reduces the duration of phases 2 and 3 of the action potential and phase 0 of the sinoatrial node action potential.
Ken BerryHOST
7:13
It also does many things that we do not know about at all.
Ken BerryHOST
7:17
so far we've documented that 84 different tissues in your body need iodine to function properly and i put a link down below so if you want to look into this in more detail you can now the next big question is how much iodine do we need i've told you what it is i've told you why we need it now let's talk about how much the official recommended daily allowance or daily intake in the united states is 150 micrograms and a microgram is one thousand a milligram so it's a tiny amount so the average adult should get a hundred and fifty micrograms according to the federal government now even the federal government realizes that pregnant women and women who are breastfeeding need more iodine than that so the RDI for pregnant women is 220 micrograms a day and for breastfeeding or lactating women is 290 micrograms a day almost double of what it is for just a regular person now right off the bat that ought to tell you that's odd wonder why pregnant women need more if it's not that big of a deal wonder why breastfeeding women need more if it's not that big of a deal they need more because it is that big of a deal and remember so basically 150 micrograms is what the average person needs in order to make their thyroid have enough so that they don't have a goiter that I talked about earlier right a swollen thyroid but what about the other glands in your body 150 micrograms a day is it is enough for your thyroid yes it's true but what about all your salivary glands your sweat glands what about your liver your pancreas your your adrenal glands what about your ovaries and testicles they need iodine as well in order to function optimally and so it's my contention that you need more than 150 micrograms a day I think the average person needs more than 290 micrograms a day so let's talk about that so some experts recommend that you should take up to 50 milligrams a day of iodine now that seems like a little much to me that would be that would be 50,000 micrograms and the RDI is 150 so that's a that's a big jump now here just to give you a frame of reference let me give you two examples the average person living in Japan is eats from 10 to 15 milligrams or 10 to 15,000 micrograms of iodine every day because they eat such a seafood heavy diet they eat lots of seafood they eat lots of sea vegetables and kelp and all these things are very rich sources of iodine and so if as some people have said eating more than a milligram of iodine a day is very dangerous then the japanese should be extinct and indeed any other population of people who live near the ocean who get anywhere from 8 to 15 milligrams of iodine a day they should die if it's that terrible they should all have hyperthyroidism or autoimmune thyroiditis or whatever it is that this the expert says oh if you get too much iodine it will harm you Example number two, there's a medication called amiodarone that doctors like me give to patients who have heart failure or severe heart problems.
Ken BerryHOST
10:30
Amiodarone has 75 milligrams of iodine in it.
Ken BerryHOST
10:35
And most people take 200 milligrams of amiodarone either once or twice a day.
Ken BerryHOST
10:40
So that means the average person taking amiodarone is getting somewhere between 75 milligrams a day and 150 milligrams a day of iodine.

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