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α-Linolenic acid

α-Linolenic acid

Chemical compoundWikipedia

Search complete. 23 mentions across 9 episodes found for "α-Linolenic acid".

Sep 5, 2026

Pal ManickamHOST
42:52
How about omega-3 fatty acids?
ArvindGUEST
42:54
Okay, so when it comes to omega-3, we do have omega-3 in the plant kingdom, but they're in the form of ALA, alpha-linolenic acid, which the body then has to convert into EPA and DHA, the long-chain ones.
ArvindGUEST
43:04
And the conversion the human body does is, depending on our genes, it changes, and it's not so efficient.
ArvindGUEST
43:09
So fish eat algae, which is a plant, and then they have omega-3 in their body.
Joel FuhrmanGUEST
24:54
At the same time, we're paying attention.
Joel FuhrmanGUEST
24:57
So that's called the ALA, the alpha-linolenic acid, the omega-3 present in those seeds and nuts.
Joel FuhrmanGUEST
25:02
So I'm using the salad dressings.
Joel FuhrmanGUEST
25:04
By the way, I'll finish that context.

16 MINS LATER

Joel FuhrmanGUEST
40:52
And the F70 in Venice Health Study showed a 12% increased risk of dementia among the vegans compared to the non-vegans.
Joel FuhrmanGUEST
40:59
And it's borne out by a couple of things here, but mostly the omega-3 index, that as you take out animal products, particularly seafood from the diet, you lower your exposure to preformed DHA and EPA.
Joel FuhrmanGUEST
41:13
And even though the body can make ALA, can make some EPA and DHA from the ALA you get from walnuts and flax seeds and green vegetables, that conversion is very genetically dependent and very inefficient, and you don't get an optimal index to protect brain size with aging as you would if you had chronic exposure to an exogenous source of DHA.
Joel FuhrmanGUEST
41:36
So supplementing with DHA for a vegan can be even more important And they make vegan DHA.
Joseph AllenHOST
19:06
If somebody does not like to eat fish or even take fish supplements because either they have an allergy or there's ethical reasons, if they eat a vegan lifestyle or they're worried about the ecology of fishing practices, then there are plant sources of omega-3.
Joseph AllenHOST
19:24
However, we don't call them EPA, DHA, we call them ALA.
Joseph AllenHOST
19:28
It stands for alpha linoleic acid, and you get this from ground flax seed, chia seed, walnuts, some canola oil, and soybeans.
Joseph AllenHOST
19:35
However, the concern is that the conversion in your body of ALA plant source omega-3 to EPA, DHA is quite low.
Joseph AllenHOST
19:45
It's somewhere around 4 to 8% in the literature.
Joseph AllenHOST
19:48
And so I'll even share in a little bit, I ate a vegan diet strictly for three months and then ate m- largely a whole food plant-based diet for, for several years, and I wasn't sure if I was getting enough omega-3.
Kieran MaguireHOST
6:02
Where is it from? What is it? Why does it matter?
Eliza FreneyGUEST
6:06
Okay, so omega-3 is a type of fatty acid So, um, the, the main types of omega-3 we talk about are ALA, EPA, and DHA.
Eliza FreneyGUEST
6:16
So most people don't realize that there are even different types of omega-3.
Eliza FreneyGUEST
6:21
Um, what you'll commonly hear people say is, "I'm taking a fish oil."
Kieran MaguireHOST
10:23
Cool.
Kieran MaguireHOST
10:23
All right.
Kieran MaguireHOST
10:24
Um, [lip smack] so EPA, DHA, ALA.
Eliza FreneyGUEST
10:29
Mm-hmm.
Richard BazinetGUEST
34:08
Because the omega-3s they're measuring are EPA and DHA in almost all of these measurements.
Richard BazinetGUEST
34:15
They call it the omega-3 index, usually.
Richard BazinetGUEST
34:17
It doesn't include that plant ALA1.
Richard BazinetGUEST
34:21
And so they show up as really, really low on that.
Richard BazinetGUEST
34:25
And you can correlate the omega-3 index inversely with health really well.
Tonje DominguezGUEST
6:22
There are a family of different fatty acids, and there are three of them that we usually talk about.
Tonje DominguezGUEST
6:28
So there is alpha-linolenic acid, ALA.
Tonje DominguezGUEST
6:32
There is EPA, and it's DHA.
Tonje DominguezGUEST
6:34
So the ALA, that is a short-chain fatty acid.
Tonje DominguezGUEST
6:38
that comes from the plant world.
Tonje DominguezGUEST
6:40
And for
speaker_1HOST
6:40
example, flaxseed can have ALA.
Tonje DominguezGUEST
6:43
And then we have EPA and DHA.
George CromackGUEST
73:14
... central nervous system.
AlexHOST
73:15
And as a parenthesis, I'm eating flax seeds and chia seeds, and my level of ALA was fine.
George CromackGUEST
73:20
Yeah.
AlexHOST
73:20
But apparently the conversion to EPA and DHA is not good.
George CromackGUEST
73:22
So not every...
George CromackGUEST
73:23
That, that, that, that's the problem, right? So those actually aren't long-chain omega-3 fat- fatty acids.
George CromackGUEST
73:28
They're omega-3, and some people do and some people don't convert ALA to, um- To, uh, long-chain omega-3 fatty acids.
George CromackGUEST
73:36
So that is a huge issue.
Gil CarvalhoHOST
1:01
you can also buy it pre-ground, that works too.
Gil CarvalhoHOST
1:03
flax seeds are so rich in omega-3s that one tablespoon covers your daily needs of ALA, the essential omega-3 we need to get from our diet.
Gil CarvalhoHOST
1:12
so that's how we grind flax seeds and store them, here's some info on grinding chia seeds and more on omega-3s in general.
Gil CarvalhoHOST
1:19
see you next time
Nelson NarcisoGUEST
31:18
But you get it from fatty fish, so sardines, anchovy, mackerel, et cetera.
Nelson NarcisoGUEST
31:24
Now, the thing about plants and fish, what differs is that in the case of a plant, you have what's called alpha-linolenic acid, ALA, which then the human body or animals convert into what's often called the active form of omega-3, which is EPA and DHA.
Nelson NarcisoGUEST
31:41
Plants do not contain EPA and DHA.
Nelson NarcisoGUEST
31:43
They only contain ALA.
Nelson NarcisoGUEST
31:44
The conversion happens in our body.
Nelson NarcisoGUEST
31:47
The challenge is that, and for a host of reasons, whether it's someone being obese or they're a smoker, if they have very high intake of omega-6 fats, the conversion efficiency of omega-3 or ALA into the preformed omega-3, EPA and DHA, isn't ideal.
Nelson NarcisoGUEST
32:05
So even if people consume adequate amounts of ALA, the plant forms of omega-3, they may still not be getting adequate amounts of EPA and DHA simply because their efficiency isn't there.
Nelson NarcisoGUEST
32:16
Now, for those that are vegan, luckily there are vegan sources of EPA and DHA from, for example, algae sourced EPA and DHA.

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