Akkermansia muciniphila

That's it, high phytochemical diet.

Here are the top five GLP-1 alternatives, allulose, PGX, berberine, acromensia, mucinophilia, and OEA, oleoethanolamide.

I think the first four have gotten very popular, the fifth one not so much yet, but I think it will be.

So I'm going to just walk you through all of these natural GLP-1 alternatives.

many of which are mediated through its impact on our gut health and, and on our liver.

And, you know, Hippocrates said it well, all health begins in the gut.

And speaking of the gut, berberine has been shown to, uh, promote the growth of acromensia, particularly acromensia mucinophilia.

This is a true intestinal superstar.

It could be several archetypes which work.

So, you know, these are the 20... distributions and compositions of microbiome that make sense, right? And so we don't, haven't quite unlocked that, but we do know that there are certain bacteria which are linked to good functional outcomes, which do certain things like Achaemansia mucinifila.

Mucinifila is mucin or mucus loving, right? That's a type of bacteria that lives in the mucus layer and actually eats the mucus layer and nourishes the, you know, the sort of microbiome that way.

So we know that and other strains are linked with certain disease states or beneficial states, bifidobacterium and lactobacilli.

A lot of that is good in the infant gut microbiome as well.

Inyectan proteínas capaces de reprogramar la manera en que se comportan tus células.

Akkermansia muciniphila es una bacteria que se correlaciona con la delgadez y la salud metabólica.

Cuando este microorganismo en particular prospera en tu intestino, es más probable que tu cuerpo mantenga un peso saludable, procese adecuadamente el azúcar y resista la inflamación.

Cuando su presencia disminuye, el síndrome metabólico se vuelve una amenaza más cercana.

Mm.

And so it, it affects, you know, the growth of organisms in the gut that are s- insulin sensitizing, like Akkermansia muciniphila, and it has this unique principle of being able to signal to genes to be less, um... to be more friendly and less hostile, so, of the, uh, the immune system.

So here would be something that most people would never even think of as a fiber and probably never heard of DCI.

Yeah.

Mm-hmm.

And then we're gonna kinda give them dumbed-down versions of it, okay? So Akkermansia muciniphila is a keystone bacteria that regulates 85% of the metabolic function in your body.

Your listeners have heard of GLP-1s, right?

Yep.

Let's talk about how this actually works.

The two bacteria involved are called Akkermansia muciniphila and Bacteroides thetaiotaomicron.

Individually, these are both really common gut bacteria, and in a lot of contexts they're considered beneficial.

But here's what the researchers found.

Bacteroides thetaiotaomicron uses an enzyme to strip protective sulfate groups off the mucus lining your gut.

And once those protective groups are removed, Akkermansia muciniphila moves in and breaks down and consumes the exposed mucus.

What makes this research stand out is that the team didn't just observe these bacteria showing up together in constipated patients.

They tested the mechanism.