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5-Hydroxytryptophan

5-Hydroxytryptophan

Chemical compoundWikipedia

Search complete. 48 mentions across 21 episodes found for "5-Hydroxytryptophan".

Sep 13, 2026

Allie MillerHOST
32:18
And if that's already declining, that may not be the best go-to line of defense.
Allie MillerHOST
32:23
So beyond relax and regulate, rather than my sleep support, which has the melatonin and the 5-HTP, which, yes, would make serotonin, I also wouldn't jump right into my thyroid optimizer, which has L-tyrosine for dopamine.
Allie MillerHOST
32:37
Those are a little bit more downstream, right? I would actually think a little bit more upstream foundational players first.
Allie MillerHOST
32:43
So we got the relax and regulate.
Julia RossGUEST
18:38
And by looking at their brain chemistry and seeing if there's some deficiency and then using the nutrients that can quickly restore any deficiency, they'll see is this a legitimate feeling or not.
Julia RossGUEST
18:49
For example, if you're low in serotonin, and you take some 5-hydroxytryptophan or 5-HTP, which is available in all the health food stores, which is just a little protein-like substance that the brain can use to make serotonin in a few minutes, if your mood improves, then you've found your true emotions.
Danielle LinHOST
19:10
So is it safe to be playing with your brain in that way, like you're popping them in and saying, oh, it's okay, I'll just take this? What's the downside? Is there any?
Julia RossGUEST
19:20
Well, the only downside is if you take some nutrients that you don't really need, and then you can get a mild headache or feel a little bit queasy, but it's very mild, and then you know immediately that you've hit the wrong target.
Julia RossGUEST
21:14
Yes, you want to say, okay, at 4 o'clock, when I start wanting the chocolate or the beer, how am I feeling? What is that? going to do for me? Is it going to be a reward, a treat, pleasure, comfort, that kind of thing? Okay, that tells us that your endorphins are low at that time of the day and you need a particular amino acid called DLPA, which will then boost your endorphin levels.
Julia RossGUEST
21:38
But other people in the afternoon are starting to get that decline that goes with the sun dropping low, especially in the wintertime, and that's your signal that it might be serotonin that's the problem.
Julia RossGUEST
21:52
So then you want to look at the low serotonin symptoms and say, do I get irritable and start feeling more negative and anxious? Is that what I'm trying to get rid of when I want the sweets or the alcohol or the pot? And if that's the case, then you're going to want to take a different nutrient that's going to build up your serotonin, the 5-HTP.
Julia RossGUEST
22:14
And some people are deficient in both at that time of day, and they need both of those amino acids.
VivekHOST
6:15
I feel recovery coming and I'm just inviting it to come faster.
VivekHOST
6:21
Black seed oil and 5-HTP is all I take these last few clean days.
VivekHOST
6:27
I don't know why, but this time is so different.
VivekHOST
6:30
I'm not gonna feel withdrawal this time, but that's because I've detached myself from kratom in my mind.
Casey ShippHOST
2:44
I can't be saying shit a lot.
Casey ShippHOST
2:45
I know SAMe and 5-HTP work really nicely as well.
Casey ShippHOST
2:50
But here's the thing.
Casey ShippHOST
2:51
You can take all the supplements.
Anna MarshHOST
37:56
So I've got one by Cytoplan, which is called Cytonite, which has got some glycine and some various other things in it.
Anna MarshHOST
38:04
And then I've got another one by A. Vogel, which is called Sleepwell, which has got a lot of lemon balm in it and 5-HTP.
Anna MarshHOST
38:12
So after the hike, I just whacked the two together.
Anna MarshHOST
38:15
I just mixed everything together, took the two magnesium glycinate and I slept really, really well.
Robin RichardsonHOST
4:18
And we were all responsible about it.
Robin RichardsonHOST
4:20
We took magnesium and all the things, 5-HTP.
Robin RichardsonHOST
4:24
And we sat in my friend's and his wife's Brooklyn apartment.
Robin RichardsonHOST
4:30
And I remember the storm was rolling in.
Mackenzie GraceHOST
18:14
They'll help find a steadier baseline, whether it's currently running too hot or too depleted.
Mackenzie GraceHOST
18:19
Amino acid or neurotransmitter support are supplements like 5-HTP, GABA, And these are important to understand because 5-HTP is blocking as a building block for serotonin.
Mackenzie GraceHOST
18:32
GABA supports a calming effect.
Mackenzie GraceHOST
18:35
And you might have seen these on Amazon or TikTok for mood or sleep, and they can genuinely help.
Andrea StaffordHOST
10:06
And while we didn't discuss their evidence today, there are two ingredients that are concerning.
Andrea StaffordHOST
10:12
one being the 5-hydroxytryptophan or 5-HTP and methylene blue.
Andrea StaffordHOST
10:18
Both can increase serotonin levels.
Andrea StaffordHOST
10:21
And when you layer these together and then add an SSRI on top, you're looking at meaningful additive serotonergic risk.
Kelly DanielsHOST
13:46
Sometimes he crashes as they wear off.
Kelly DanielsHOST
13:49
He also has side effects like sleeping problems and irritability.
Kelly DanielsHOST
13:53
And she pulls up the stack and it contains 5-HTP, tyrosine, zinc, fish oil, saffron extract, and lion's mane.
Kelly DanielsHOST
14:01
Okay.
Peggy TanosGUEST
64:08
I took SAMe.
Peggy TanosGUEST
64:10
I took 5-HTP.
Peggy TanosGUEST
64:12
That was the best one.
Peggy TanosGUEST
64:13
I took L-theanine.
Peggy TanosGUEST
64:26
And that was great too.
Peggy TanosGUEST
64:27
I don't even know what was in it, but it was all holistic and natural.
Peggy TanosGUEST
64:30
But the thing that worked the best was the 5-HTP.
Nicole DoranHOST
64:32
Yeah.
Laura MazuccaGUEST
55:03
I started weaning myself off these things and started implementing things to rebuild my serotonin.
Laura MazuccaGUEST
55:09
5-HTP, all the precursors that are there to allow you to have your own serotonin replenishment and regulate your moods.
Laura MazuccaGUEST
55:19
I went on this massive protocol.
Laura MazuccaGUEST
55:21
I started working out.

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