5-Hydroxytryptophan
Chemical compoundWikipedia
48
MENTIONS
21
EPISODES
21
PODCASTS
Search complete. 48 mentions across 21 episodes found for "5-Hydroxytryptophan".
Sep 13, 2026
Episode 512: ADHD with estrogen and progesterone decline?
A
32:18Allie MillerHOST
And if that's already declining, that may not be the best go-to line of defense.
A
32:23Allie MillerHOST
So beyond relax and regulate, rather than my sleep support, which has the melatonin and the 5-HTP, which, yes, would make serotonin, I also wouldn't jump right into my thyroid optimizer, which has L-tyrosine for dopamine.
A
32:37Allie MillerHOST
Those are a little bit more downstream, right? I would actually think a little bit more upstream foundational players first.
A
32:43Allie MillerHOST
So we got the relax and regulate.
The Mood Cure –Julia Ross, M.A.
J
18:38Julia RossGUEST
And by looking at their brain chemistry and seeing if there's some deficiency and then using the nutrients that can quickly restore any deficiency, they'll see is this a legitimate feeling or not.
J
18:49Julia RossGUEST
For example, if you're low in serotonin, and you take some 5-hydroxytryptophan or 5-HTP, which is available in all the health food stores, which is just a little protein-like substance that the brain can use to make serotonin in a few minutes, if your mood improves, then you've found your true emotions.
D
19:10Danielle LinHOST
So is it safe to be playing with your brain in that way, like you're popping them in and saying, oh, it's okay, I'll just take this? What's the downside? Is there any?
J
19:20Julia RossGUEST
Well, the only downside is if you take some nutrients that you don't really need, and then you can get a mild headache or feel a little bit queasy, but it's very mild, and then you know immediately that you've hit the wrong target.
J
21:14Julia RossGUEST
Yes, you want to say, okay, at 4 o'clock, when I start wanting the chocolate or the beer, how am I feeling? What is that? going to do for me? Is it going to be a reward, a treat, pleasure, comfort, that kind of thing? Okay, that tells us that your endorphins are low at that time of the day and you need a particular amino acid called DLPA, which will then boost your endorphin levels.
J
21:38Julia RossGUEST
But other people in the afternoon are starting to get that decline that goes with the sun dropping low, especially in the wintertime, and that's your signal that it might be serotonin that's the problem.
J
21:52Julia RossGUEST
So then you want to look at the low serotonin symptoms and say, do I get irritable and start feeling more negative and anxious? Is that what I'm trying to get rid of when I want the sweets or the alcohol or the pot? And if that's the case, then you're going to want to take a different nutrient that's going to build up your serotonin, the 5-HTP.
J
22:14Julia RossGUEST
And some people are deficient in both at that time of day, and they need both of those amino acids.
Kratom Withdrawal Completely Annihilated Their Minds
V
6:15VivekHOST
I feel recovery coming and I'm just inviting it to come faster.
V
6:21VivekHOST
Black seed oil and 5-HTP is all I take these last few clean days.
V
6:27VivekHOST
I don't know why, but this time is so different.
V
6:30VivekHOST
I'm not gonna feel withdrawal this time, but that's because I've detached myself from kratom in my mind.
#204: From Refrigerator-Body to Hotmomz: The Brutal Truth About 'Getting Hot'
C
2:44Casey ShippHOST
I can't be saying shit a lot.
C
2:45Casey ShippHOST
I know SAMe and 5-HTP work really nicely as well.
C
2:50Casey ShippHOST
But here's the thing.
C
2:51Casey ShippHOST
You can take all the supplements.
Episode 158: What Happened After My Longest Hike Since Illness
A
37:56Anna MarshHOST
So I've got one by Cytoplan, which is called Cytonite, which has got some glycine and some various other things in it.
A
38:04Anna MarshHOST
And then I've got another one by A. Vogel, which is called Sleepwell, which has got a lot of lemon balm in it and 5-HTP.
A
38:12Anna MarshHOST
So after the hike, I just whacked the two together.
A
38:15Anna MarshHOST
I just mixed everything together, took the two magnesium glycinate and I slept really, really well.
Did You Design Your Life?
R
4:18Robin RichardsonHOST
And we were all responsible about it.
R
4:20Robin RichardsonHOST
We took magnesium and all the things, 5-HTP.
R
4:24Robin RichardsonHOST
And we sat in my friend's and his wife's Brooklyn apartment.
R
4:30Robin RichardsonHOST
And I remember the storm was rolling in.
Your Supplement Cabinet Is a Graveyard (Here's How to Fix That)
M
18:14Mackenzie GraceHOST
They'll help find a steadier baseline, whether it's currently running too hot or too depleted.
M
18:19Mackenzie GraceHOST
Amino acid or neurotransmitter support are supplements like 5-HTP, GABA, And these are important to understand because 5-HTP is blocking as a building block for serotonin.
M
18:32Mackenzie GraceHOST
GABA supports a calming effect.
M
18:35Mackenzie GraceHOST
And you might have seen these on Amazon or TikTok for mood or sleep, and they can genuinely help.
ADHD Supplement Stacking: Are More Supplements Better?
A
10:06Andrea StaffordHOST
And while we didn't discuss their evidence today, there are two ingredients that are concerning.
A
10:12Andrea StaffordHOST
one being the 5-hydroxytryptophan or 5-HTP and methylene blue.
A
10:18Andrea StaffordHOST
Both can increase serotonin levels.
A
10:21Andrea StaffordHOST
And when you layer these together and then add an SSRI on top, you're looking at meaningful additive serotonergic risk.
K
13:46Kelly DanielsHOST
Sometimes he crashes as they wear off.
K
13:49Kelly DanielsHOST
He also has side effects like sleeping problems and irritability.
K
13:53Kelly DanielsHOST
And she pulls up the stack and it contains 5-HTP, tyrosine, zinc, fish oil, saffron extract, and lion's mane.
K
14:01Kelly DanielsHOST
Okay.
Fan Favorite Episode: Postpartum Depression, Anti-Aging Without Surgery & Manifestation with Peggy Tanos (RHOC)
P
64:08Peggy TanosGUEST
I took SAMe.
P
64:10Peggy TanosGUEST
I took 5-HTP.
P
64:12Peggy TanosGUEST
That was the best one.
P
64:13Peggy TanosGUEST
I took L-theanine.
P
64:26Peggy TanosGUEST
And that was great too.
P
64:27Peggy TanosGUEST
I don't even know what was in it, but it was all holistic and natural.
P
64:30Peggy TanosGUEST
But the thing that worked the best was the 5-HTP.
N
64:32Nicole DoranHOST
Yeah.
#435 Today's Boondoggle- From Mind to Muscle with Navy Veteran Laura Mazucca
L
55:03Laura MazuccaGUEST
I started weaning myself off these things and started implementing things to rebuild my serotonin.
L
55:09Laura MazuccaGUEST
5-HTP, all the precursors that are there to allow you to have your own serotonin replenishment and regulate your moods.
L
55:19Laura MazuccaGUEST
I went on this massive protocol.
L
55:21Laura MazuccaGUEST
I started working out.
11 more episodes mention 5-Hydroxytryptophan.
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