
5-HT3 receptor
ProteinWikipedia
7
MENTIONS
4
EPISODES
3
PODCASTS
Search complete. 7 mentions across 4 episodes found for "5-HT3 receptor".
Oct 20, 2026
Why Antidepressants Take Weeks to Work
C
1:59CarlosHOST
Many second-generation antipsychotics, including risperidone and olanzapine, antagonize this receptor alongside dopamine receptors.
C
2:12CarlosHOST
Including our 5-HT3 receptor contributes to nausea and vomiting.
C
2:18CarlosHOST
So here you're looking at adenositrone, an antiemetic, which blocks this receptor.
C
2:23CarlosHOST
So 5-HT1A participates in anxiety and mood regulation.
C
2:27CarlosHOST
5-H2A is associated with perception and cortical signaling.
C
2:31CarlosHOST
This is the P pain perception component.
C
2:34CarlosHOST
And 5-HT3 contributes to nausea.
C
2:36CarlosHOST
That's gastrointestinal functioning and vomiting.
Serotonin and the Brain: Why Antidepressants Take Weeks to Work
S
1:59speaker_3HOST
Many second-generation antipsychotics, including risperidone and olanzapine, antagonize this receptor alongside dopamine receptors.
S
2:11speaker_3HOST
Including our 5-HT3 receptor contributes to nausea and vomiting.
S
2:18speaker_3HOST
So here you're looking at adenositrone, an antiemetic, which blocks this receptor.
S
2:23speaker_3HOST
So 5-HT1A participates in anxiety and mood regulation.
S
2:27speaker_3HOST
5-H2A is associated with perception and cortical signaling.
S
2:31speaker_3HOST
This is the P pain perception component.
S
2:34speaker_3HOST
And 5-HT3 contributes to nausea.
S
2:36speaker_3HOST
That's gastrointestinal functioning and vomiting.
Antidepressant Augmentation: What to Add and Why
D
7:12Daniel SouterHOST
Mirtazapine blocks alpha-2 receptors in the brain, which leads to downstream increases in norepinephrine and serotonin release.
D
7:22Daniel SouterHOST
It also does block several serotonin receptors, particularly 5-HT2 and 5-HT3, and it strongly blocks histamine H1 receptors.
D
7:32Daniel SouterHOST
That antihistamine effect is what explains the sleep and appetite-inducing properties.
D
7:38Daniel SouterHOST
So it again has a very different profile from an SS or SNRI, which is part of the rationale for combining them.
Why Antidepressants Take Weeks to Work
C
1:59CarlosHOST
Many second-generation antipsychotics, including risperidone and olanzapine, antagonize this receptor alongside dopamine receptors.
C
2:11CarlosHOST
Including our 5-HT3 receptor contributes to nausea and vomiting.
C
2:18CarlosHOST
So here you're looking at adenositrone, an antiemetic, which blocks this receptor.
C
2:22CarlosHOST
So 5-HT1A participates in anxiety and mood regulation.
C
2:27CarlosHOST
5-H2A is associated with perception and cortical signaling.
C
2:31CarlosHOST
This is the P pain perception component.
C
2:33CarlosHOST
And 5-HT3 contributes to nausea, that's gastrointestinal functioning, and vomiting.
C
2:39CarlosHOST
These three receptor associations because they connect neurobiology with clinical prescribing, that's why it's important to remember.