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2-Deoxy-D-glucose

2-Deoxy-D-glucose

Search complete. 1 mention across 1 episode found for "2-Deoxy-D-glucose".

Oct 9, 2026

Eric KossoffGUEST
14:09
There was a lot of discussion about, like, should we call these, like, metabolism-based therapies, right? But, like, it gets to sort of like, are these still a diet therapy? Are you still changing your diet? And, and you are, okay? You know, there are other therapies that are, like, targeting metabolism, really looking at the ketogenic diet mechanistically.
Eric KossoffGUEST
14:30
So ketone esters, 2DG.
Eric KossoffGUEST
14:33
There's a lot of interesting therapies that are based on the ketogenic diet but are not changing your diet, if that makes sense.
Eric KossoffGUEST
14:40
So as a field, we, we actually have been back and forth for a few years but decided for many reasons, also just for parent recognition and patient recognition, there is some appeal to families, like you were saying, right? Like, they like the idea that they can change their diet to help their own seizures, right? And so for that reason, along with several others, we've decided at least, at least for now, to keep calling these ketogenic diet therapies as opposed to metabolism therapies.

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