The Francis Crick Institute

Which is obviously a bit disappointing for lots of people.

Where we see a bit more success is where there's a reason, you know, if you acquire a, you know, Big Pharma acquires a business, but that business has a tie to Cambridge University or a tie to Francis Crick Institute or an institution.

And they're doing some sort of clever, you know, there's a sort of, there's a bigger story to the IP that's being created there.

what then happens is you're seeing a sort of hub-and-spoke model.

Hello, I'm Professor Brian Cox.

Welcome to the second series of A Question of Science recorded here at the Francis Crick Institute in London.

Today, we're asking whether we're ruled by our guts.

Now, that might sound a bit flippant, but over the past decade, there have been major advances in our understanding of our gut.

And now on with the podcast.

I'm a feminist, but I went into the Francis Crick Institute this week and felt intellectually intimidated by a building.

LAUGHTER

I'm a feminist, but I feel the urge to put a blouse and slacks on Sidney Sweeney.

King's Cross could be quite rough.

But right now in King's Cross, there's some absolutely extraordinary things.

Now, you can stroll past the British Library to the Francis Crick Institute, where they're literally just curing diseases that you haven't even got yet.

so that you can walk casually in a relaxed fashion through fountains, past Central Saint Martins, over to the Queer Britain Museum and encounter books, science, fashion, art, before you've even decided where to have lunch.

Hello, I'm Professor Brian Cox.

Welcome to A Question of Science, recorded here at the Francis Crick Institute in London.

Now, in the first series of this show, we asked whether we can harness AI for good and concluded that it depends on a lot of things, but particularly on your definition of good.

But today, we'll be looking specifically about how AI is transforming medicine and asking what are the benefits and the risks of involving AI in one of the most personal aspects of our lives.

Hello, I'm Samara Trialich.

I'm a cancer physician and a research scientist.

I'm a group leader here at the Francis Crick Institute, and as of last year, I became the director of the Cancer Research UK Manchester Institute and an oncologist at the Christie NHS Foundation Trust.

And this is our panel.

And this is from first authors Nicolas Weiland and Bethania Garcia-Cassani and corresponding authors Adrian Hayday and Miguel Muñoz Ruiz.

And this is from King's College London and the Francis Crick Institute.

And in this paper, what they're trying to do is, as I say, understand what exactly is the role of the gamma-ZTCR.

Because for alpha-beta T cells, I think by now it's pretty clear they recognize peptides presented, like mostly peptides presented in the context of MHC molecules.

effect because even if you get it, it won't be that bad.

The Francis Crick Institute in London conducted the investigation and concluded that first author, Kevin Nigg, N-G, was responsible for the fake data and imaging.

Nigg, who worked for the Institute in 2022 when the paper was published, has admitted responsibility.

According to the note, these freaking people should be in jail.

[intro music] Hello, I'm Professor Brian Cox.

Welcome to A Question of Science, recorded here at the Francis Crick Institute in London.

This is the podcast where a panel of experts tackle your questions on the biggest scientific challenges facing society today.

In this new series, we'll be covering a whole range of subjects from how AI is transforming medicine to the state of our oceans.

Let me state that again.

Researchers at Francis Crick, C-R-I-C-K Institute, very famous institute, have found that gut inflammation, there's your sugar, there's your caffeine, there's your alcohol, there's your steak, there's your french fries, that causes inflammation in your gut.

can reactivate dormant breast cancer cells in a mouse model of bone marrow.

Their study published in Cell Reports suggests that changes needed to produce more immune cells can also create conditions that favor cancer growth.